Factors Affecting Accuracy and Precision in PET Volume Imaging

Volume imaging positron emission tomographic (PET) scanners with no septa and a large axial acceptance angle offer several advantages over multiring PET scanners. A volume imaging scanner combines high sensitivity with fine axial sampling and spatial resolution. The fine axial sampling minimizes the...

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Bibliographic Details
Published in:Journal of cerebral blood flow and metabolism 1991-03, Vol.11 (S1), p.A38-A44
Main Authors: Karp, Joel S., Daube-Witherspoon, Margaret E., Muehllehner, Gerd
Format: Article
Language:English
Subjects:
550601 - Medicine- Unsealed Radionuclides in Diagnostics
ACCURACY
ALGORITHMS
Biological and medical sciences
BODY
BRAIN
Brain - diagnostic imaging
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
EMISSION COMPUTED TOMOGRAPHY
Investigative techniques, diagnostic techniques (general aspects)
MATHEMATICAL LOGIC
Medical sciences
NERVOUS SYSTEM
ORGANS
POSITRON COMPUTED TOMOGRAPHY
RADIOLOGY AND NUCLEAR MEDICINE
Radionuclide investigations
RESOLUTION
SCATTERING
Scattering, Radiation
SENSITIVITY ANALYSIS
SPATIAL RESOLUTION
TOMOGRAPHY
Tomography, Emission-Computed - methods
Tomography, Emission-Computed - standards
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Summary:Volume imaging positron emission tomographic (PET) scanners with no septa and a large axial acceptance angle offer several advantages over multiring PET scanners. A volume imaging scanner combines high sensitivity with fine axial sampling and spatial resolution. The fine axial sampling minimizes the partial volume effect, which affects the measured concentration of an object. Even if the size of an object is large compared to the slice spacing in a multiring scanner, significant variation in the concentration is measured as a function of the axial position of the object. With a volume imaging scanner, it is necessary to use a three-dimensional reconstruction algorithm in order to avoid variations in the axial resolution as a function of the distance from the center of the scanner. In addition, good energy resolution is needed in order to use a high energy threshold to reduce the coincident scattered radiation.
ISSN:0271-678X
1559-7016
DOI:10.1038/jcbfm.1991.35