Assessment of the Health Impact of Environmental Exposure to Cadmium: Contribution of the Epidemiologic Studies Carried Out in Belgium

Data from epidemiologic studies on the health effects of cadmium carried out in Belgium are reported and discussed. Overall results have shown that Cd accumulation in the human body has increased significantly in polluted areas. Three main groups of thresholds have been identified. The epidemiologic...

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Bibliographic Details
Published in:Environmental research 1993-08, Vol.62 (2), p.200-206
Main Authors: Lauwerys, R.R., Bernard, A.M., Buchet, J.P., Roels, H.A.
Format: Article
Language:English
Subjects:
550500 - Metabolism
560300 - Chemicals Metabolism & Toxicology
Adult
ADULTS
AGE GROUPS
Aged
BASIC BIOLOGICAL SCIENCES
BELGIUM
Biological and medical sciences
BODY
CADMIUM
Cadmium - adverse effects
Cadmium - pharmacokinetics
Cadmium - urine
DEVELOPED COUNTRIES
DISTRIBUTION
ELEMENTS
ENVIRONMENTAL EXPOSURE
Environmental Exposure - adverse effects
Environmental pollutants toxicology
EUROPE
Female
General aspects
Humans
Kidney - metabolism
KIDNEYS
Male
Maximum Allowable Concentration
MAXIMUM PERMISSIBLE EXPOSURE
Medical sciences
METALS
Middle Aged
ORGANS
Proteinuria - chemically induced
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RISK ASSESSMENT
SAFETY STANDARDS
TISSUE DISTRIBUTION
Toxicology
WESTERN EUROPE
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Description
Summary:Data from epidemiologic studies on the health effects of cadmium carried out in Belgium are reported and discussed. Overall results have shown that Cd accumulation in the human body has increased significantly in polluted areas. Three main groups of thresholds have been identified. The epidemiologic data suggest that, for the general population, the amount of Cd accumulatd in the body should preferentially not exceed a level corresponding to a urinary excretion of 2 mu g Cd/24 h. To prevent the concentration of Cd in the renal cortex from reaching 50 ppm at age 50, a daily intake of Cd in nonsmokers should not exceed 1 mu g Cd/kg body weight.
ISSN:0013-9351
1096-0953
DOI:10.1006/enrs.1993.1105