Measurement of Free Ammonia Produced by X Irradiation of Glycylglycine in Aqueous Solution

• Published in: Radiation research 1990-03, Vol.121 (3), p.257-261
• Main Authors: Yoshida, Hiroko, Bolch, Wesley E., Jacobson, K. Bruce, Turner, James E.
• Format: Article
• Language: English
• Subjects: 560120 - Radiation Effects on Biochemicals, Cells, & Tissue Culture; AMMONIA; AQUEOUS SOLUTIONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; Biological and medical sciences; BIOSYNTHESIS; CHEMISTRY; COBALT 60; COBALT ISOTOPES; COMPARATIVE EVALUATIONS; Dipeptides - radiation effects; DISPERSIONS; ELECTROMAGNETIC RADIATION; Electrons; Free radicals; Fundamental and applied biological sciences. Psychology; GLYCYLGLYCINE; Glycylglycine - radiation effects; HYDRIDES; HYDROGEN COMPOUNDS; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; Irradiation; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MINUTES LIVING RADIOISOTOPES; MIXTURES; Molecular interactions; NITROGEN COMPOUNDS; NITROGEN HYDRIDES; NUCLEI; NUCLEOTIDES; Nucleotides - metabolism; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; Oxygen; PEPTIDES; PROBABILITY; PROTEINS; RADIATION EFFECTS; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT; RADIATIONS; RADIOCHEMISTRY; RADIOISOTOPES; Radiolysis; Solar X rays; Solutes; SOLUTIONS; Space life sciences; SYNTHESIS; Tissues, organs and organisms biophysics; X RADIATION; YEARS LIVING RADIOISOT
• ISSN: 0033-7587; 1938-5404
• DOI: 10.2307/3577774

This research was initiated to test the validity of predictions based on Monte Carlo calculations of the effect of ionizing radiation on a simple dipeptide. The mechanism for the formation of ammonia, proposed by Garrison, Sokol, and Bennett-Corniea (Radiat. Res. 53, 376-384, 1973), was reevaluated by measuring the yields under deoxygenated and oxygenated conditions. Although free ammonia was formed under both conditions, the yields were different, depending on the concentrations of solute and molecular oxygen. The reaction probabilities of the specific interactions of free radicals formed in pure water with solute and oxygen are discussed to account for the observed difference. Our results obtained after low-dose-rate X irradiation are compared with those obtained by Garrison et al. after high-dose-rate 60 Co γ irradiation.