Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices

Three aspects of microchip electrophoresis devices are discussed. Bonding of the substrate and cover slip is accomplished by hydrolizing the surfaces and then joining and annealing them. Pinched sample loading is found to be superior with regard to temporal stability and plug length.

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Bibliographic Details
Published in:Analytical chemistry (Washington) 1994-04, Vol.66 (7), p.1107-1113
Main Authors: Jacobson, Stephen C, Hergenroder, Roland, Koutny, Lance B, Warmack, R. J, Ramsey, J. Michael
Format: Article
Language:English
Subjects:
400105 - Separation Procedures
400400 - Electrochemistry
400500 - Photochemistry
990200 - Mathematics & Computers
AMINES
AMMONIUM COMPOUNDS
AMMONIUM FLUORIDES
AMMONIUM HALIDES
Analytical chemistry
Blood vessels
CARBOXYLIC ACIDS
Chemistry
Chromatographic methods and physical methods associated with chromatography
DYES
ELECTROPHORESIS
ETCHING
Exact sciences and technology
FLUORIDES
FLUORINE COMPOUNDS
GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
GLASS
HALIDES
HALOGEN COMPOUNDS
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROFLUORIC ACID
HYDROGEN COMPOUNDS
HYDROGEN PEROXIDE
INORGANIC ACIDS
INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY
MATHEMATICAL MODELS
MINERALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
Other chromatographic methods
OXIDE MINERALS
OXYGEN COMPOUNDS
PEROXIDES
QUARTZ
REAGENTS
RHODAMINES
SURFACE FINISHING
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Description
Summary:Three aspects of microchip electrophoresis devices are discussed. Bonding of the substrate and cover slip is accomplished by hydrolizing the surfaces and then joining and annealing them. Pinched sample loading is found to be superior with regard to temporal stability and plug length.
ISSN:0003-2700
1520-6882
DOI:10.1021/ac00079a028