124PRIMARY MALIGNANT CHEST WALL TUMOURS: ANALYSIS OF 40 PATIENTS

• Published in: Interactive cardiovascular and thoracic surgery 2014-10, Vol.19 (suppl_1), p.S38-S38
• Main Authors: Bagheri, R., Haghi, S.Z., Kalantari, M.R., Attar, A. Sharifian, Salehi, M., Tabari, A., Soudaneh, M.
• Format: Article
• Language: English
• ISSN: 1569-9293; 1569-9285
• DOI: 10.1093/icvts/ivu276.124

Objectives: Primary chest wall tumours originate from different constructions of the thoracic wall. We report our experience on primary thoracic tumour resection and reconstruction. Methods: We performed a retrospective review on 40 patients with malignant primary chest wall tumour from 1989 to 2009. Patients were evaluated in terms of age, sex, clinical presentation, type of imaging, tissue diagnosis methods, pathology, surgical technique, early complications, hospital mortality, prevalence of recurrence and distant metastases, additional treatment, 3-year survival and factors affecting survival. Results: Male/female = 1, median age = 43.72 years. Mass and soft tissue sarcoma were the most common symptoms and pathology, respectively. Resection without reconstruction was performed in 5 patients and 35 patients (87.5%) had extensive resection and reconstruction with rotatory muscular flap, prosthetic mesh and/or cement; 12.5% (5/40) of patients received neoadjuvant therapy and 75% (30/40) received adjuvant therapy. The 3-year survival rate was 65%. Recurrences occurred in 24 patients (60%); 14 developed local recurrences, 10 developed distant metastases. The primary treatment modality for local and distant recurrences was surgical resection; 10 underwent repeated resection, 9 adjuvant therapy and 5 were underwent lung metastasectomy. The most common distant metastasis site was lung (n = 7). Factors that affected survival were type of pathology and evidence of distant metastasis. Conclusion: Surgery with wide margin is a safe technique for treatment of primary chest wall tumours with acceptable morbidity and mortality.