096AORTIC VALVE REPAIR IN ASYMPTOMATIC PATIENTS WITH SEVERE AORTIC VALVE REGURGITATION: LONG-TERM RESULTS

• Published in: Interactive cardiovascular and thoracic surgery 2014-10, Vol.19 (suppl_1), p.S29-S29
• Main Authors: Fattouch, K., Castrovinci, S., Murana, G., Dioguardi, P., Guccione, F., Moscarelli, M., Nasso, G., Speziale, G.
• Format: Article
• Language: English
• ISSN: 1569-9293; 1569-9285
• DOI: 10.1093/icvts/ivu276.96

Objectives: Patients with aortic regurgitation may develop irreversible left ventricle dysfunction while still asymptomatic and several studies have clearly shown adverse outcomes. The aim of the study was to assess the clinical outcomes of aortic valve repair in patients with chronic severe aortic regurgitation without symptoms. Methods: Between February 2003 and December 2013, 124 asymptomatic patients with chronic severe aortic regurgitation underwent aortic valve repair. Causes of disease were annulo-aortic-ectasia in 51 patients, aneurysm in 39, bicuspid in 26 and Marfan in 8. Correction of aortic leaflet prolapse was done by central cusp plication in 40 patients, by free edge reinforcement with Gore-Tex suture in 35 and by our approach “the chordae technique” in 49. The study endpoints were to assess the impact of aortic valve repair on freedom from cardiac-related deaths and cardiac- or valve-related events. We evaluated the late outcomes according to the preoperative left ventricular ejection fraction (LVEF) and to left ventricular end diastolic diameter/body surface area (LVEDD/BSA, mm/m2). The mean follow-up was 68 ± 20 months. Results: No in-hospital death occurred. Overall late death happened in 3 patients (2.4%), in particular cardiac-related death in 2 patients. Overall survival rate was 96.7%. Ten-year survival rate in asymptomatic patients with LVEF >50% and with LVEF ≤50% were 98.4% and 89.9%, respectively (P < 0.05). Patients with LVEDD/BSA