Cognitive Functioning in Gulf War Illness

A comprehensive neuropsychological battery was administered to 48 veterans with Gulf War Illness (GWI) characterized by severe fatigue (GV-F) and 39 healthy veterans (GV-H). Subjects were matched on intelligence and did not differ on age, gender, race, and alcohol consumption. Compared to GVs-H, GVs...

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Bibliographic Details
Published in:Journal of clinical and experimental neuropsychology 2001-04, Vol.23 (2), p.240-249
Main Authors: Lange, G., Tiersky, L.A., DeLuca, J., Scharer, J.B., Policastro, T., Fiedler, N., Morgan, J.E., Natelson, B.H.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Attention
Biological and medical sciences
Case-Control Studies
Cognition
Cognition Disorders - diagnosis
Cognition Disorders - etiology
Fatigue Syndrome, Chronic - etiology
Fatigue Syndrome, Chronic - psychology
Female
Humans
Male
Medical sciences
Models, Psychological
Neuropsychological Tests
Organic mental disorders. Neuropsychology
Persian Gulf Syndrome - complications
Persian Gulf Syndrome - diagnosis
Persian Gulf Syndrome - psychology
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
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Summary:A comprehensive neuropsychological battery was administered to 48 veterans with Gulf War Illness (GWI) characterized by severe fatigue (GV-F) and 39 healthy veterans (GV-H). Subjects were matched on intelligence and did not differ on age, gender, race, and alcohol consumption. Compared to GVs-H, GVs-F were significantly impaired on four tasks: three attention, concentration, information processing tasks and one measure of ion and conceptualization. After considering the presence of post-war Axis I psychopathology, GWI remained a significant predictor of cognitive performance on one of the attention, concentration, and information processing tasks and one abstraction and conceptualization measure. Performance on the remaining two attention, concentration, and information processing tasks was only significantly predicted by Axis I psychopathology with post-war onset. The results suggest that Gulf War Illness is associated with some aspects of cognitive dysfunction in Gulf Veterans, over and above the contribution of psychopathology.
ISSN:1380-3395
1744-411X
DOI:10.1076/jcen.23.2.240.1208