HIV Adolescents Show Improved Immune Function Following Massage Therapy

HIV+ adolescents (M CD4=466 mm3) recruited from a large urban university hospital's outpatient clinic were randomly assigned to receive massage therapy (n = 12) or progressive muscle relaxation (n = 12) two-times per week for 12 weeks. To assess treatment effects, participants were assessed for...

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Bibliographic Details
Published in:International journal of neuroscience 2001, Vol.106 (1-2), p.35-45
Main Authors: Diego, Miguel A., Field, Tiffany, Hernandez-Reif, Maria, Shaw, Kimberly, Friedman, Lawrence, Ironson, Gail
Format: Article
Language:English
Subjects:
Adolescent
Anxiety
Anxiety - etiology
Biological and medical sciences
CD4 antigen
CD56 antigen
CD8 antigen
Depression
Depressive Disorder, Major - etiology
Female
HIV
HIV Seropositivity - immunology
HIV Seropositivity - psychology
Human immunodeficiency virus
Human viral diseases
Humans
Immunity
Infectious diseases
Killer Cells, Natural - immunology
Lymphocyte Count
Male
Massage
massage therapy
Medical sciences
Psychometrics
Random Allocation
Relaxation
Relaxation Therapy
T-Lymphocytes - immunology
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:HIV+ adolescents (M CD4=466 mm3) recruited from a large urban university hospital's outpatient clinic were randomly assigned to receive massage therapy (n = 12) or progressive muscle relaxation (n = 12) two-times per week for 12 weeks. To assess treatment effects, participants were assessed for depression, anxiety and immune changes before and after treatment the 12 weeks treatment period. Adolescents who received massage therapy versus those who experienced relaxation therapy reported feeling less anxious and they were less depressed, and showed enhanced immune function by the end of the 12 week study. Immune changes included increased Natural Killer cell number (CD56) and CD56+CD3-. In addition, the HIV disease progression markers CD4/CD8 ratio and CD4 number showed an increase for the massage therapy group only.
ISSN:0020-7454
1563-5279
1543-5245
DOI:10.3109/00207450109149736