Improvement in Health Care Utilization and Pulmonary Function with Fluticasone Propionate in Patients with Steroid-Dependent Asthma at a National Asthma Referral Center

The impact of switching from other inhaled corticosteroids to fluticasone propionate was studied in patients with severe oral-steroid-dependent asthma over a 1-year period. In this open-label prospective study, patients on maintenance doses of oral and inhaled steroids were referred to a national as...

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Bibliographic Details
Published in:The Journal of asthma 2001-01, Vol.38 (5), p.405-412
Main Authors: Wenzel, Sally E., Morgan, Kate, Griffin, Rachel, Stanford, Richard, Edwards, Lisa, Wamboldt, Frederick S., Rogenes, Paula
Format: Article
Language:English
Subjects:
Administration, Inhalation
Administration, Oral
Adolescent
Adult
Androstadienes - administration & dosage
Androstadienes - economics
Androstadienes - therapeutic use
Anti-Asthmatic Agents - administration & dosage
Anti-Asthmatic Agents - economics
Anti-Asthmatic Agents - therapeutic use
Asthma
Asthma - economics
Asthma - prevention & control
Biological and medical sciences
Colorado
Costs and Cost Analysis
Female
Fluticasone
Fluticasone propionate
Health care utilization
Humans
Inhaled corticosteroid
Male
Medical sciences
Middle Aged
Outpatient Clinics, Hospital - utilization
Pharmacology. Drug treatments
Prednisone - administration & dosage
Prospective Studies
Pulmonary function
Referral and Consultation
Respiratory Function Tests
Respiratory system
Treatment Outcome
United States
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Description
Summary:The impact of switching from other inhaled corticosteroids to fluticasone propionate was studied in patients with severe oral-steroid-dependent asthma over a 1-year period. In this open-label prospective study, patients on maintenance doses of oral and inhaled steroids were referred to a national asthma treatment center and were switched from their previous inhaled corticosteroid to fluticasone propionate 880 μg BID. Compared with data collected from the year prior to enrollment, treatment with fluticasone propionate resulted in significant improvements in pulmonary function, oral steroid requirements, and health resource utilization. In addition, five patients were completely weaned off oral steroids.
ISSN:0277-0903
1532-4303
DOI:10.1081/JAS-100001495