Are Some Ear Drops Ototoxic or Potentially Ototoxic?

In this article we review the literature concerning the capacity of certain substances to cause ototoxicity when administered topically. The ototoxicity experimentally observed in animals only occurs in humans under certain circumstances. It is concluded that many of these products, which are common...

Full description

Saved in:
Bibliographic Details
Published in:Acta oto-laryngologica 2001, Vol.121 (5), p.565-568
Main Authors: PALOMAR GARCIA, V, PALOMAR ASENJO, V
Format: Article
Language:English
Subjects:
4-Quinolones
Administration, Topical
Aminoglycosides
Animals
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - adverse effects
Anti-Infective Agents - administration & dosage
Anti-Infective Agents - adverse effects
Anti-Inflammatory Agents - administration & dosage
Anti-Inflammatory Agents - adverse effects
Antifungal Agents - administration & dosage
Antifungal Agents - adverse effects
Biological and medical sciences
Drug toxicity and drugs side effects treatment
Ear Drop Ototoxicity Topical Ear Treatment
Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology
Humans
Medical sciences
Non tumoral diseases
Otitis Media, Suppurative - drug therapy
Otorhinolaryngology. Stomatology
Pharmacology. Drug treatments
Solvents - administration & dosage
Solvents - adverse effects
Steroids
Toxicity: respiratory system, ent, stomatology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this article we review the literature concerning the capacity of certain substances to cause ototoxicity when administered topically. The ototoxicity experimentally observed in animals only occurs in humans under certain circumstances. It is concluded that many of these products, which are commonly used for treatment in humans, are ototoxic in animals and may also be ototoxic in humans. Therefore, the use of other substances which have the same action but are not ototoxic is recommended.
ISSN:0001-6489
1651-2251
DOI:10.1080/00016480119705