INTERLEUKIN-6 (IL-6) IN SEMINAL PLASMA OF INFERTILE MEN, AND LIPID PEROXIDATION OF THEIR SPERM

Concentrations of tumor necrosis factor- &#102 (TNF- &#102 ) and interleukin-6 (IL-6) in seminal fluid, as well as levels of sperm lipid membrane peroxidation, were investigated in fertile and infertile men. Semen samples, obtained by masturbation from 37 infertile and 14 fertile men, were e...

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Bibliographic Details
Published in:Archives of andrology 2001, Vol.47 (2), p.97-101
Main Authors: Camejo, M. I., Segnini, A., Proverbio, F.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Birth control
Gynecology. Andrology. Obstetrics
Humans
Infertility, Male - metabolism
Interleukin
Interleukin-6 - metabolism
Lipid Peroxidation
Male
Male Infertility
Malondialdehyde - metabolism
Medical sciences
Semen
Semen - metabolism
Spermatozoa
Spermatozoa - metabolism
Sterility. Assisted procreation
Tumor Necrosis Factor-ALPHA
Tumor Necrosis Factor-alpha - metabolism
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Summary:Concentrations of tumor necrosis factor- &#102 (TNF- &#102 ) and interleukin-6 (IL-6) in seminal fluid, as well as levels of sperm lipid membrane peroxidation, were investigated in fertile and infertile men. Semen samples, obtained by masturbation from 37 infertile and 14 fertile men, were examined for the presence of TNF- &#102 and IL-6. The level of lipid peroxidation of the sperm membrane was measured by determining malondialdehyde (MDA) formation. The correlation between the IL-6 and the TNF- &#102 concentrations in seminal plasma with the levels of lipid peroxidation of the sperm membranes was statistically evaluated. The IL-6 concentration in seminal plasma of infertile men was significantly higher than that of fertile men ( p
ISSN:0955-3002
0148-5016
1362-3095
1521-0375
DOI:10.1080/014850101316901280