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Stability of Cephalosporin Prodrug Esters in Human Intestinal Juice: Implications for Oral Bioavailability
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Published in: | Antimicrobial Agents and Chemotherapy 1998-10, Vol.42 (10), p.2602-2606 |
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container_end_page | 2606 |
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container_title | Antimicrobial Agents and Chemotherapy |
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creator | STOECKEL, K HOFHEINZ, W LANEURY, J. P DUCHENE, P SHEDLOFSKY, S BLOUIN, R. A |
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doi_str_mv | 10.1128/aac.42.10.2602 |
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Print ISSN:
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.42.10.2602</identifier><identifier>PMID: 9756762</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Administration, Oral ; Adult ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Biological Availability ; Cefpodoxime Proxetil ; Ceftizoxime - analogs & derivatives ; Ceftizoxime - pharmacokinetics ; Cefuroxime - analogs & derivatives ; Cefuroxime - pharmacokinetics ; Cephalosporins ; Cephalosporins - pharmacokinetics ; Drug Stability ; Humans ; Intestinal Mucosa ; Intestinal Mucosa - metabolism ; Male ; Medical sciences ; Pharmacology ; Pharmacology. Drug treatments ; Prodrugs ; Prodrugs - pharmacokinetics</subject><ispartof>Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2602-2606</ispartof><rights>1999 INIST-CNRS</rights><rights>Copyright © 1998 American Society for Microbiology</rights><rights>Copyright © 1998, American Society for Microbiology 1998</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a531t-8165d87d819da3c69e1d528e43518f2478631752569c9123d0728ec1ee3cf66f3</citedby><cites>FETCH-LOGICAL-a531t-8165d87d819da3c69e1d528e43518f2478631752569c9123d0728ec1ee3cf66f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.asm.org/doi/pdf/10.1128/AAC.42.10.2602$$EPDF$$P50$$Gasm2$$H</linktopdf><linktohtml>$$Uhttps://journals.asm.org/doi/full/10.1128/AAC.42.10.2602$$EHTML$$P50$$Gasm2$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3188,3189,27924,27925,52751,52752,52753,53791,53793</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1581750$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9756762$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>STOECKEL, K</creatorcontrib><creatorcontrib>HOFHEINZ, W</creatorcontrib><creatorcontrib>LANEURY, J. P</creatorcontrib><creatorcontrib>DUCHENE, P</creatorcontrib><creatorcontrib>SHEDLOFSKY, S</creatorcontrib><creatorcontrib>BLOUIN, R. A</creatorcontrib><title>Stability of Cephalosporin Prodrug Esters in Human Intestinal Juice: Implications for Oral Bioavailability</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>Antimicrob. Agents Chemother</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Administration, Oral</subject><subject>Adult</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Biological Availability</subject><subject>Cefpodoxime Proxetil</subject><subject>Ceftizoxime - analogs & derivatives</subject><subject>Ceftizoxime - pharmacokinetics</subject><subject>Cefuroxime - analogs & derivatives</subject><subject>Cefuroxime - pharmacokinetics</subject><subject>Cephalosporins</subject><subject>Cephalosporins - pharmacokinetics</subject><subject>Drug Stability</subject><subject>Humans</subject><subject>Intestinal Mucosa</subject><subject>Intestinal Mucosa - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology</subject><subject>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>9756762</pmid><doi>10.1128/aac.42.10.2602</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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ispartof | Antimicrobial Agents and Chemotherapy, 1998-10, Vol.42 (10), p.2602-2606 |
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source | American Society for Microbiology; Open Access: PubMed Central |
subjects | Administration, Oral Adult Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Biological Availability Cefpodoxime Proxetil Ceftizoxime - analogs & derivatives Ceftizoxime - pharmacokinetics Cefuroxime - analogs & derivatives Cefuroxime - pharmacokinetics Cephalosporins Cephalosporins - pharmacokinetics Drug Stability Humans Intestinal Mucosa Intestinal Mucosa - metabolism Male Medical sciences Pharmacology Pharmacology. Drug treatments Prodrugs Prodrugs - pharmacokinetics |
title | Stability of Cephalosporin Prodrug Esters in Human Intestinal Juice: Implications for Oral Bioavailability |
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