Usefulness of lipids, lipoprotein(a) and fibrinogen measurements in identifying subjects at risk of occlusive complications following vascular and endovascular surgery

The study was designed to establish the usefulness of measuring lipoprotein(a) [Lp(a)], total cholesterol, triglycerides, low-density lipoprotein [LDL]-cholesterol, high-density lipoprotein [HDL]-cholesterol, total-to-HDL-cholesterol ratio and fibrinogen in identifying subjects at risk of occlusive...

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Bibliographic Details
Published in:Scandinavian journal of clinical and laboratory investigation 1998, Vol.58 (6), p.497-504
Main Author: G Lippi, G F Veraldi, V Dorucci, R Dusi, O Ruzzenente, C Brentegani, G Guidi, C Cordiano
Format: Article
Language:English
Subjects:
Angioplasty, Balloon
Aorta - surgery
Arterial Occlusive Diseases - blood
Arterial Occlusive Diseases - diagnosis
Arterial Occlusive Diseases - etiology
Biological and medical sciences
Carotid Arteries - surgery
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Endarterectomy
Fibrinogen - analysis
Humans
Lipids - blood
Lipoprotein(a) - blood
Medical sciences
Postoperative Complications - blood
Postoperative Complications - diagnosis
Retinal Vein Occlusion - blood
Retinal Vein Occlusion - diagnosis
Retinal Vein Occlusion - etiology
Risk Factors
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the heart
Vascular Diseases - surgery
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Summary:The study was designed to establish the usefulness of measuring lipoprotein(a) [Lp(a)], total cholesterol, triglycerides, low-density lipoprotein [LDL]-cholesterol, high-density lipoprotein [HDL]-cholesterol, total-to-HDL-cholesterol ratio and fibrinogen in identifying subjects at risk of occlusive complications following vascular and endovascular surgery, including primary successful ileofemoral percutaneous transluminal angioplasty, infrainguinal and aortic bypass graft and carotid endarterectomy. A total of 68 volunteers subjected to vascular and endovascular surgery were recruited to the study. Six months after successful interventions, no occlusive complications verified by angiography were observed in 45 patients (66%; No-restenosis group), whereas significant restenosis or reocclusion occurred in 23 patients (34%; Restenosis group). Significant lower concentrations of Lp(a) (p=0.032), total cholesterol (p
ISSN:0036-5513
1502-7686
DOI:10.1080/00365519850186300