Synthesis and biological evaluation of 3-heterocyclyl-7,8,9,10-tetrahydro-(7,10-ethano)-1,2,4-triazolo[3,4-a]phthalazin es and analogues as subtype-selective inverse agonists for the GABAAα5 benzodiazepine binding site

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Bibliographic Details
Published in:Journal of medicinal chemistry 2004, Vol.47 (14), p.3642-3657
Main Authors: STREET, Leslie J, STERNFELD, Francine, DAWSON, Gerard R, BROMIDGE, Frances A, WAFFORD, Keith A, SEABROOK, Guy R, THOMPSON, Sally A, MARSHALL, George, PILLAI, Goplan V, CASTRO, Josh L, ATACK, John R, MACLEOD, Angus M, JELLEY, Richard A, REEVE, Austin J, CARLING, Robert W, MOORE, Kevin W, MCKERNAN, Ruth M, SOHAL, Bindi, COOK, Susan, PIKE, Andrew
Format: Article
Language:English
Subjects:
Biological and medical sciences
Gabaergic and benzodiazepinic system
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
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ISSN:0022-2623
1520-4804