TMC125, a Novel Next-Generation Nonnucleoside Reverse Transcriptase Inhibitor Active against Nonnucleoside Reverse Transcriptase Inhibitor-Resistant Human Immunodeficiency Virus Type 1

• Published in: Antimicrobial Agents and Chemotherapy 2004-12, Vol.48 (12), p.4680-4686
• Main Authors: ANDRIES, Koen, AZIJN, Hilde, DE BETHUNE, Marie-Pierre, THIELEMANS, Theo, LUDOVICI, Donald, KUKLA, Michael, HEERES, Jan, JANSSEN, Paul, DE CORTE, Bart, VINGERHOETS, Johan, PAUWELS, Rudi
• Format: Article
• Language: English
• Subjects: Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Biological and medical sciences; Cell Line; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Viral; Genotype; HIV-1; HIV-1 - drug effects; HIV-1 - genetics; Human immunodeficiency virus 1; Human immunodeficiency virus 2; Humans; Medical sciences; Microbial Sensitivity Tests; Microsomes, Liver - metabolism; Mutagenesis, Site-Directed; Pharmacology. Drug treatments; Pyridazines; Pyridazines - pharmacokinetics; Pyridazines - pharmacology; Reverse Transcriptase Inhibitors; Reverse Transcriptase Inhibitors - pharmacokinetics; Reverse Transcriptase Inhibitors - pharmacology
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.48.12.4680-4686.2004

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