Inhibitory effect of five plant extracts on heart rates of rats

Aqueous extracts of Loeselia mexicana, Calendula officinalis, Teloxys graveolens, Oenothera roseae and Castilleja tenuiflora were tested on the heart activity of male Wistar rats. It was found that C. officinalis, T. graveolens, L. mexicana and O. roseae inhibited the heart contractile activity risi...

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Bibliographic Details
Published in:PTR. Phytotherapy research 1998, Vol.12 (S1), p.S49-S50
Main Authors: Pérez-Gutiérrez, Salud, Vargas-Solís, Rosario, Zavala S., Miguel, Pérez-G., Cuauhtemoc, Pérez-G., Rosa M.
Format: Article
Language:English
Subjects:
Biological and medical sciences
General pharmacology
heart
Inhibitory activity
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
plants
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Summary:Aqueous extracts of Loeselia mexicana, Calendula officinalis, Teloxys graveolens, Oenothera roseae and Castilleja tenuiflora were tested on the heart activity of male Wistar rats. It was found that C. officinalis, T. graveolens, L. mexicana and O. roseae inhibited the heart contractile activity rising to 100% inhibition at doses of 0.3, 0.5, 0.7 and 1.0 mg/mL respectively. However, C. tenuiflora increases the rate of the heart activity at doses from 0.1 to 0.6 mg/mL. © 1998 John Wiley & Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/(SICI)1099-1573(1998)12:1+3.0.CO;2-B