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Human Immunodeficiency Virus Protease Inhibitors Serve as Substrates for Multidrug Transporter Proteins MDR1 and MRP1 but Retain Antiviral Efficacy in Cell Lines Expressing These Transporters
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| Published in: | Antimicrobial Agents and Chemotherapy 1998-12, Vol.42 (12), p.3157-3162 |
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| Main Authors: | , , , |
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| container_end_page | 3162 |
| container_issue | 12 |
| container_start_page | 3157 |
| container_title | Antimicrobial Agents and Chemotherapy |
| container_volume | 42 |
| creator | SRINIVAS, R. V MIDDLEMAS, D FLYNN, P FRIDLAND, A |
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| doi_str_mv | 10.1128/AAC.42.12.3157 |
| format | article |
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1752 N Street N.W. • Washington DC 20036
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Print ISSN:
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</description><subject>Antibiotics, Antineoplastic - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. 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Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Antiviral Agents - metabolism</topic><topic>Antiviral Agents - pharmacology</topic><topic>ATP Binding Cassette Transporter, Subfamily B, Member 1</topic><topic>ATP Binding Cassette Transporter, Subfamily B, Member 1 - biosynthesis</topic><topic>ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism</topic><topic>ATP-Binding Cassette Transporters</topic><topic>ATP-Binding Cassette Transporters - biosynthesis</topic><topic>ATP-Binding Cassette Transporters - metabolism</topic><topic>Biological and medical sciences</topic><topic>Cell Line</topic><topic>Doxorubicin - pharmacology</topic><topic>Drug Resistance, Microbial</topic><topic>Drug Resistance, Multiple</topic><topic>Flow Cytometry</topic><topic>Fluoresceins</topic><topic>Fluorescent Dyes</topic><topic>HIV Protease Inhibitors</topic><topic>HIV Protease Inhibitors - metabolism</topic><topic>HIV Protease Inhibitors - pharmacology</topic><topic>HIV-1 - drug effects</topic><topic>Human immunodeficiency virus 1</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Multidrug Resistance-Associated Proteins</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>9835508</pmid><doi>10.1128/AAC.42.12.3157</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 1998-12, Vol.42 (12), p.3157-3162 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_pascalfrancis_primary_1644666 |
| source | American Society for Microbiology; PubMed Central |
| subjects | Antibiotics, Antineoplastic - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Antiviral Agents - metabolism Antiviral Agents - pharmacology ATP Binding Cassette Transporter, Subfamily B, Member 1 ATP Binding Cassette Transporter, Subfamily B, Member 1 - biosynthesis ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism ATP-Binding Cassette Transporters ATP-Binding Cassette Transporters - biosynthesis ATP-Binding Cassette Transporters - metabolism Biological and medical sciences Cell Line Doxorubicin - pharmacology Drug Resistance, Microbial Drug Resistance, Multiple Flow Cytometry Fluoresceins Fluorescent Dyes HIV Protease Inhibitors HIV Protease Inhibitors - metabolism HIV Protease Inhibitors - pharmacology HIV-1 - drug effects Human immunodeficiency virus 1 Humans Medical sciences Multidrug Resistance-Associated Proteins Pharmacology. Drug treatments T-Lymphocytes - drug effects T-Lymphocytes - microbiology |
| title | Human Immunodeficiency Virus Protease Inhibitors Serve as Substrates for Multidrug Transporter Proteins MDR1 and MRP1 but Retain Antiviral Efficacy in Cell Lines Expressing These Transporters |
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