Linezolid in the treatment of brain abscess due to Peptostreptococcus

Brain abscesses can be caused by bacteria, fungi, and parasites. Among bacteria, anaerobic organisms include the Bacteroides species group, Fusobacterium, Peptostreptococcus, and Propionibacterium. In these cases, a 4-week course of parenteral penicillin/cefalosporin and metronidazole is the standar...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 2006, Vol.38 (3), p.203-205
Main Authors: Salin, Federica, Vianello, Fabrizio, Manara, Renzo, Morelli, Erika, Cattelan, Annamaria, Scarin, Marino, Sgarabotto, Dino
Format: Article
Language:English
Subjects:
Acetamides - therapeutic use
Adult
Anti-Infective Agents - therapeutic use
Antibacterial agents
Antibiotics. Antiinfectious agents. Antiparasitic agents
Bacterial diseases
Bacterial diseases of the nervous system. Bacterial myositis
Bacteroides
Biological and medical sciences
Brain Abscess - drug therapy
Brain Abscess - microbiology
Fusobacterium
Gram-Positive Bacterial Infections - drug therapy
Gram-Positive Bacterial Infections - microbiology
Human bacterial diseases
Humans
Infectious diseases
Linezolid
Male
Medical sciences
Oxazolidinones - therapeutic use
Peptostreptococcus
Peptostreptococcus - drug effects
Pharmacology. Drug treatments
Propionibacterium
Thalamus - microbiology
Treatment Outcome
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Summary:Brain abscesses can be caused by bacteria, fungi, and parasites. Among bacteria, anaerobic organisms include the Bacteroides species group, Fusobacterium, Peptostreptococcus, and Propionibacterium. In these cases, a 4-week course of parenteral penicillin/cefalosporin and metronidazole is the standard of treatment. We describe a case of brain abscess secondary to anaerobic infection with Peptostreptococcus, which was successfully treated with parenteral and oral linezolid after failure of standard therapy.
ISSN:0036-5548
1651-1980
DOI:10.1080/00365540500322270