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Pharmacokinetics and metabolism studies on 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction
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Published in: | Bioorganic & medicinal chemistry letters 2006, Vol.16 (4), p.872-875 |
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container_title | Bioorganic & medicinal chemistry letters |
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creator | JONES, Philip ATACK, John R SZETO, Nicola WAFFORD, Keith A MACLEOD, Angus M BRAUN, Matthew P CATO, Brian P CHAMBERS, Mark S O'CONNOR, Desmond COOK, Susan M HOBBS, Sarah C MAXEY, Robert SZEKERES, Helen J |
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subjects | Biological and medical sciences Contrast media. Radiopharmaceuticals Gabaergic and benzodiazepinic system Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments |
title | Pharmacokinetics and metabolism studies on 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy) pyrazolo[1,5-d][1,2,4]triazine, a functionally selective GABAA α5 inverse agonist for cognitive dysfunction |
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