The Role of Physician Characteristics in Clinical Trial Acceptance: Testing Pathways of Influence

Eight videotaped vignettes were developed that assessed the effects of three physician-related experimental variables (in a 2 × 2 × 2 factorial design) on clinical trial (CT) knowledge, video knowledge, information processing, CT beliefs, affective evaluations (attitudes), and CT acceptance. It was...

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Bibliographic Details
Published in:Journal of health communication 2006-03, Vol.11 (2), p.199-218
Main Authors: Curbow, Barbara, Fogarty, Linda A., McDonnell, Karen A., Chill, Julia, Scott, Lisa Benz
Format: Article
Language:English
Subjects:
Biological and medical sciences
Breast Neoplasms
Clinical Trials as Topic
Doctors
Female
Health
Health Knowledge, Attitudes, Practice
Health participants
Health promotion
Health technology assessment
Humans
Medical sciences
Middle Aged
Miscellaneous
Patient Acceptance of Health Care
Physician's Role
Power relations
Public health. Hygiene
Public health. Hygiene-occupational medicine
Referral and Consultation
Social influence
United States
Videotape Recording
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Summary:Eight videotaped vignettes were developed that assessed the effects of three physician-related experimental variables (in a 2 × 2 × 2 factorial design) on clinical trial (CT) knowledge, video knowledge, information processing, CT beliefs, affective evaluations (attitudes), and CT acceptance. It was hypothesized that the physician variables (community versus academic-based affiliation, enthusiastic versus neutral presentation of the trial, and new versus previous relationship with the patient) would serve as communication cues that would interrupt message processing, leading to lower knowledge gain but more positive beliefs, attitudes, and CT acceptance. A total of 262 women (161 survivors and 101 controls) participated in the study. The manipulated variables primarily influenced the intermediary variables of post-test CT beliefs and satisfaction with information rather than knowledge or information processing. Multiple regression results indicated that CT acceptance was associated with positive post-CT beliefs, a lower level of information processing, satisfaction with information, and control status. Based on these results, CT acceptance does not appear to be based on a rational decision-making model; this has implications for both the ethics of informed consent and research conceptual models.
ISSN:1081-0730
1087-0415
DOI:10.1080/10810730500526703