Discovery of N-[(1R,2S,5S)-2-{[(5-chloroindol-2-yl)carbonylamino}-5-(dimethylcarbamoyl)cyclohexyl]-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide hydrochloride : A novel, potent and orally active direct inhibitor of factor Xa

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry 2009, Vol.17 (3), p.1193-1206
Main Authors: NAGATA, Tsutomu, YOSHINO, Toshiharu, OSANAI, Ken, SUZUKI, Makoto, KANNO, Hideyuki, HAGINOYA, Noriyasu, YOSHIKAWA, Kenji, NAGAMOCHI, Masatoshi, KOBAYASHI, Syozo, KOMORIYA, Satoshi, YOKOMIZO, Aki, MUTO, Ryo, YAMAGUCHI, Mitsuhiro
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Medical sciences
Pharmacology. Drug treatments
Online Access:Get full text
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ISSN:0968-0896
1464-3391