Discovery of N-(3-Fluorophenyl)-1-[4-([(3S)-3-methyl-1-piperazinyl]methyl)phenylacetyl]-4-piperidinamine (GSK962040), the First Small Molecule Motilin Receptor Agonist Clinical Candidate

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Published in:Journal of medicinal chemistry 2009, Vol.52 (4), p.1180-1189
Main Authors: WESTAWAY, Susan M, BROWN, Samantha L, THOMPSON, Mervyn, LAWLESS, Kirk, MCKAY, Fiona, MUIR, Alison I, BARFORD, Jonathan M, CLUFF, Chermaine, MAHMOOD, Sadhia R, MATTHEWS, Kim L, MOHAMED, Shiyam, SMITH, Beverley, FELL, Stephen C. M, STEVENS, Alexander J, BOLTON, Victoria J, JARVIE, Emma M, SANGER, Gareth J, JOHNSON, Christopher N, MACPHERSON, David T, MITCHELL, Darren J, MYATT, James W, STANWAY, Steven J, SEAL, Jon T, STEMP, Geoffrey
Format: Article
Language:English
Subjects:
Biological and medical sciences
Digestive system
Medical sciences
Pharmacology. Drug treatments
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container_end_page 1189
container_issue 4
container_start_page 1180
container_title Journal of medicinal chemistry
container_volume 52
creator WESTAWAY, Susan M
BROWN, Samantha L
THOMPSON, Mervyn
LAWLESS, Kirk
MCKAY, Fiona
MUIR, Alison I
BARFORD, Jonathan M
CLUFF, Chermaine
MAHMOOD, Sadhia R
MATTHEWS, Kim L
MOHAMED, Shiyam
SMITH, Beverley
FELL, Stephen C. M
STEVENS, Alexander J
BOLTON, Victoria J
JARVIE, Emma M
SANGER, Gareth J
JOHNSON, Christopher N
MACPHERSON, David T
MITCHELL, Darren J
MYATT, James W
STANWAY, Steven J
SEAL, Jon T
STEMP, Geoffrey
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Biological and medical sciences
Digestive system
Medical sciences
Pharmacology. Drug treatments
title Discovery of N-(3-Fluorophenyl)-1-[4-([(3S)-3-methyl-1-piperazinyl]methyl)phenylacetyl]-4-piperidinamine (GSK962040), the First Small Molecule Motilin Receptor Agonist Clinical Candidate
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