Design, synthesis, and structure-activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline y-secretase inhibitors

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2009, Vol.19 (17), p.4920-4923
Main Authors: TRUONG, Anh P, AUBELE, Danielle L, GAROFALO, Albert W, KEIM, Pamela S, JING WU, DAPPEN, Michael S, WONG, Marina, GOLDBACH, Erich, QUINN, Kevin P, SAUER, John-Michael, BRIGHAM, Elizabeth F, WALLACE, William, PROBST, Gary D, NGUYEN, Lan, HEMPHILL, Susanna S, BOVA, Michael P, BASI, Guriqbal, NEITZEL, Martin L, SEMKO, Chris M, BOWERS, Simeon, DRESSEN, Darren, HOM, Roy K, KONRADI, Andrei W, SHAM, Hing L
Format: Article
Language:English
Subjects:
Biological and medical sciences
Medical sciences
Neuropharmacology
Pharmacology. Drug treatments
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopharmacology
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ISSN:0960-894X
1464-3405