Two new homoisoflavonoids from the fibrous roots of Ophiopogon japonicus (Thunb.) Ker-Gawl

Two new homoisoflavonoids ophiopogonone D (1) and ophiopogonanone G (2) were isolated from the fibrous roots of Ophiopogon japonicus. The structures of these two compounds were determined on the basis of spectroscopic means including HR-ESI-MS, 1D, and 2D NMR experiments. The cytotoxic activities of...

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Bibliographic Details
Published in:Journal of asian natural products research 2009-10, Vol.11 (10), p.876-879
Main Authors: Duan, Chang-Ling, Kang, Zhi-Yun, Lin, Cheng-Ren, Jiang, Yong, Liu, Jian-Xun, Tu, Peng-Fei
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Phytogenic - chemistry
Antineoplastic Agents, Phytogenic - isolation & purification
Antineoplastic Agents, Phytogenic - pharmacology
Biological and medical sciences
cytotoxicity
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal - chemistry
Drugs, Chinese Herbal - isolation & purification
Drugs, Chinese Herbal - pharmacology
Flowers & plants
General pharmacology
HeLa Cells
homoisoflavonoids
Humans
Isoflavones - chemistry
Isoflavones - isolation & purification
Isoflavones - pharmacology
Liliaceae
Medical sciences
Molecular Structure
Natural products
Nuclear Magnetic Resonance, Biomolecular
Ophiopogon - chemistry
Ophiopogon japonicus (Thunb.) Ker-Gawl
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Roots - chemistry
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Summary:Two new homoisoflavonoids ophiopogonone D (1) and ophiopogonanone G (2) were isolated from the fibrous roots of Ophiopogon japonicus. The structures of these two compounds were determined on the basis of spectroscopic means including HR-ESI-MS, 1D, and 2D NMR experiments. The cytotoxic activities of 1 and 2 against Hela and Hep2 cells are described.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020903093161