Studies on antiinflammatory effect of Cassia tora leaf extract (fam. Leguminosae)

The antiinflammatory effect of the methanol extract of the leaves of Cassia tora was investigated against carrageenin, histamine, serotonin and dextran‐induced rat hind paw oedema. It exhibited significant antiinflammatory activity against all these agents. The extract (400 mg/kg) showed maximum inh...

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Bibliographic Details
Published in:Phytotherapy research 1998-05, Vol.12 (3), p.221-223
Main Authors: Maity, Tapan Kumar, Mandal, Subhash C., Mukherjee, Pulok K., Saha, K., Das, J., Pal, M., Saha, B. P.
Format: Article
Language:English
Subjects:
antiinflammatory activity
Biological and medical sciences
Cassia tora
General pharmacology
mediator induced
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
phenylbutazone
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Summary:The antiinflammatory effect of the methanol extract of the leaves of Cassia tora was investigated against carrageenin, histamine, serotonin and dextran‐induced rat hind paw oedema. It exhibited significant antiinflammatory activity against all these agents. The extract (400 mg/kg) showed maximum inhibition of oedema of 40.33%, 31.37%, 53.57% and 29.15% at the end of 3 h with carrageenin, dextran, histamine and serotonin‐induced rat paw oedema, respectively. Using a chronic test, the granuloma pouch in rats, the extract exhibited a 48.13% reduction in granuloma weight. © 1998 John Wiley & Sons, Ltd.
ISSN:0951-418X
1099-1573
DOI:10.1002/(SICI)1099-1573(199805)12:3<221::AID-PTR221>3.0.CO;2-L