Emergence of VIM-12 in Enterobacter cloacae

Detection of the blaVIM₋₁₂ gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due t...

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Bibliographic Details
Published in:Journal of Clinical Microbiology 2010-09, Vol.48 (9), p.3414-3415
Main Authors: Panopoulou, Maria, Alepopoulou, Eleonora, Ikonomidis, Alexandros, Grapsa, Anastasia, Paspalidou, Eleni, Kartali-Ktenidou, Sofia
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - pharmacology
Bacteriology
beta-Lactam Resistance
beta-Lactamases - biosynthesis
beta-Lactamases - genetics
beta-Lactams - pharmacology
Biological and medical sciences
Enterobacter cloacae
Enterobacter cloacae - drug effects
Enterobacter cloacae - enzymology
Enterobacter cloacae - genetics
Enterobacter cloacae - isolation & purification
Enterobacteriaceae Infections - microbiology
Fundamental and applied biological sciences. Psychology
Humans
Integrons
Microbial Sensitivity Tests
Microbiology
Miscellaneous
Plasmids - analysis
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Summary:Detection of the blaVIM₋₁₂ gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.
ISSN:0095-1137
1098-660X
DOI:10.1128/JCM.00843-10