ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES

The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices....

Full description

Saved in:
Bibliographic Details
Published in:Journal of liquid chromatography & related technologies 2011-08, Vol.34 (14), p.1442-1458
Main Authors: Trehy, Michael L., Ye, Wei, Hadwiger, Michael E., Moore, Terry W., Allgire, James F., Woodruff, Jeffrey T., Ahadi, Shafiq S., Black, John C., Westenberger, Benjamin J.
Format: Article
Language:English
Subjects:
anatabine
Biological and medical sciences
cigarette
cotinine
e-cigarette
Medical sciences
nicotine
smokeless
Tobacco, tobacco smoking
Toxicology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873
cites cdi_FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873
container_end_page 1458
container_issue 14
container_start_page 1442
container_title Journal of liquid chromatography & related technologies
container_volume 34
creator Trehy, Michael L.
Ye, Wei
Hadwiger, Michael E.
Moore, Terry W.
Allgire, James F.
Woodruff, Jeffrey T.
Ahadi, Shafiq S.
Black, John C.
Westenberger, Benjamin J.
description The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination. Samples of nicotine containing products were purchased via the internet from NJOY, Smoking Everywhere, CIXI, and Johnson Creek. Electronic cigarette devices were purchased from NJOY, Smoking Everywhere, and CIXI. The results from the testing found that (1) the nicotine content labeling was not accurate with some manufacturers, (2) nicotine is present in the "smoke" from electronic cigarettes, and (3) nicotine related impurities contents in cartridges and refills were found to vary by electronic cigarette manufacturer.
doi_str_mv 10.1080/10826076.2011.572213
format article
fullrecord <record><control><sourceid>proquest_pasca</sourceid><recordid>TN_cdi_pascalfrancis_primary_24718993</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2726591711</sourcerecordid><originalsourceid>FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873</originalsourceid><addsrcrecordid>eNp9kF1PgzAUhonRxDn9B140Md7JbAuFcmUI62YjAwNdoleklJFsYWOWLWb_3k7cLr05X3nec3Jey7pHcIQghc8mYA_63ghDhEbExxg5F9YAEQxt031cmtog9pG5tm66bgUh8gkmA2sfJmH8mfMcpBPAYhaJLE14BCI-DTMmBANRmImMj6csfwIZm_A4BnkazwVPEzMJkzHIZ-kbA5M0A0aZCp6w3_G5yVgcCjYGfPY-z7jgLL-1rmrZdIu7vzy05hMmolc7Tqc8CmNbuQ7a2crDgVthSYMSK8ellJYo8KgH3bKslEeJ6xPiBVVZ1nVtfvdKSAhelFJRRTH1naH10O_d6vZrv-h2xard6405WSDoQB8jTLGh3J5Suu06vaiLrV6upT4YqDgaXJwMLo4GF73BRvb4t1x2Sja1lhu17M5a7PqIBsGRe-m55aZu9Vp-t7qpip08NK0-iZx_L_0AxEeDgg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1030721282</pqid></control><display><type>article</type><title>ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES</title><source>Taylor and Francis Science and Technology Collection</source><creator>Trehy, Michael L. ; Ye, Wei ; Hadwiger, Michael E. ; Moore, Terry W. ; Allgire, James F. ; Woodruff, Jeffrey T. ; Ahadi, Shafiq S. ; Black, John C. ; Westenberger, Benjamin J.</creator><creatorcontrib>Trehy, Michael L. ; Ye, Wei ; Hadwiger, Michael E. ; Moore, Terry W. ; Allgire, James F. ; Woodruff, Jeffrey T. ; Ahadi, Shafiq S. ; Black, John C. ; Westenberger, Benjamin J.</creatorcontrib><description>The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination. Samples of nicotine containing products were purchased via the internet from NJOY, Smoking Everywhere, CIXI, and Johnson Creek. Electronic cigarette devices were purchased from NJOY, Smoking Everywhere, and CIXI. The results from the testing found that (1) the nicotine content labeling was not accurate with some manufacturers, (2) nicotine is present in the "smoke" from electronic cigarettes, and (3) nicotine related impurities contents in cartridges and refills were found to vary by electronic cigarette manufacturer.</description><identifier>ISSN: 1082-6076</identifier><identifier>EISSN: 1520-572X</identifier><identifier>DOI: 10.1080/10826076.2011.572213</identifier><identifier>CODEN: JLCTFC</identifier><language>eng</language><publisher>Colchester: Taylor &amp; Francis Group</publisher><subject>anatabine ; Biological and medical sciences ; cigarette ; cotinine ; e-cigarette ; Medical sciences ; nicotine ; smokeless ; Tobacco, tobacco smoking ; Toxicology</subject><ispartof>Journal of liquid chromatography &amp; related technologies, 2011-08, Vol.34 (14), p.1442-1458</ispartof><rights>2011</rights><rights>2015 INIST-CNRS</rights><rights>Copyright Taylor &amp; Francis Ltd. 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873</citedby><cites>FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=24718993$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Trehy, Michael L.</creatorcontrib><creatorcontrib>Ye, Wei</creatorcontrib><creatorcontrib>Hadwiger, Michael E.</creatorcontrib><creatorcontrib>Moore, Terry W.</creatorcontrib><creatorcontrib>Allgire, James F.</creatorcontrib><creatorcontrib>Woodruff, Jeffrey T.</creatorcontrib><creatorcontrib>Ahadi, Shafiq S.</creatorcontrib><creatorcontrib>Black, John C.</creatorcontrib><creatorcontrib>Westenberger, Benjamin J.</creatorcontrib><title>ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES</title><title>Journal of liquid chromatography &amp; related technologies</title><description>The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination. Samples of nicotine containing products were purchased via the internet from NJOY, Smoking Everywhere, CIXI, and Johnson Creek. Electronic cigarette devices were purchased from NJOY, Smoking Everywhere, and CIXI. The results from the testing found that (1) the nicotine content labeling was not accurate with some manufacturers, (2) nicotine is present in the "smoke" from electronic cigarettes, and (3) nicotine related impurities contents in cartridges and refills were found to vary by electronic cigarette manufacturer.</description><subject>anatabine</subject><subject>Biological and medical sciences</subject><subject>cigarette</subject><subject>cotinine</subject><subject>e-cigarette</subject><subject>Medical sciences</subject><subject>nicotine</subject><subject>smokeless</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><issn>1082-6076</issn><issn>1520-572X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNp9kF1PgzAUhonRxDn9B140Md7JbAuFcmUI62YjAwNdoleklJFsYWOWLWb_3k7cLr05X3nec3Jey7pHcIQghc8mYA_63ghDhEbExxg5F9YAEQxt031cmtog9pG5tm66bgUh8gkmA2sfJmH8mfMcpBPAYhaJLE14BCI-DTMmBANRmImMj6csfwIZm_A4BnkazwVPEzMJkzHIZ-kbA5M0A0aZCp6w3_G5yVgcCjYGfPY-z7jgLL-1rmrZdIu7vzy05hMmolc7Tqc8CmNbuQ7a2crDgVthSYMSK8ellJYo8KgH3bKslEeJ6xPiBVVZ1nVtfvdKSAhelFJRRTH1naH10O_d6vZrv-h2xard6405WSDoQB8jTLGh3J5Suu06vaiLrV6upT4YqDgaXJwMLo4GF73BRvb4t1x2Sja1lhu17M5a7PqIBsGRe-m55aZu9Vp-t7qpip08NK0-iZx_L_0AxEeDgg</recordid><startdate>20110815</startdate><enddate>20110815</enddate><creator>Trehy, Michael L.</creator><creator>Ye, Wei</creator><creator>Hadwiger, Michael E.</creator><creator>Moore, Terry W.</creator><creator>Allgire, James F.</creator><creator>Woodruff, Jeffrey T.</creator><creator>Ahadi, Shafiq S.</creator><creator>Black, John C.</creator><creator>Westenberger, Benjamin J.</creator><general>Taylor &amp; Francis Group</general><general>Taylor &amp; Francis</general><general>Taylor &amp; Francis Ltd</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SE</scope><scope>7SR</scope><scope>7TB</scope><scope>7U5</scope><scope>7U7</scope><scope>8BQ</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H8G</scope><scope>JG9</scope><scope>KR7</scope><scope>L7M</scope><scope>P64</scope></search><sort><creationdate>20110815</creationdate><title>ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES</title><author>Trehy, Michael L. ; Ye, Wei ; Hadwiger, Michael E. ; Moore, Terry W. ; Allgire, James F. ; Woodruff, Jeffrey T. ; Ahadi, Shafiq S. ; Black, John C. ; Westenberger, Benjamin J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>anatabine</topic><topic>Biological and medical sciences</topic><topic>cigarette</topic><topic>cotinine</topic><topic>e-cigarette</topic><topic>Medical sciences</topic><topic>nicotine</topic><topic>smokeless</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Trehy, Michael L.</creatorcontrib><creatorcontrib>Ye, Wei</creatorcontrib><creatorcontrib>Hadwiger, Michael E.</creatorcontrib><creatorcontrib>Moore, Terry W.</creatorcontrib><creatorcontrib>Allgire, James F.</creatorcontrib><creatorcontrib>Woodruff, Jeffrey T.</creatorcontrib><creatorcontrib>Ahadi, Shafiq S.</creatorcontrib><creatorcontrib>Black, John C.</creatorcontrib><creatorcontrib>Westenberger, Benjamin J.</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Mechanical &amp; Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Toxicology Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Copper Technical Reference Library</collection><collection>Materials Research Database</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of liquid chromatography &amp; related technologies</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Trehy, Michael L.</au><au>Ye, Wei</au><au>Hadwiger, Michael E.</au><au>Moore, Terry W.</au><au>Allgire, James F.</au><au>Woodruff, Jeffrey T.</au><au>Ahadi, Shafiq S.</au><au>Black, John C.</au><au>Westenberger, Benjamin J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES</atitle><jtitle>Journal of liquid chromatography &amp; related technologies</jtitle><date>2011-08-15</date><risdate>2011</risdate><volume>34</volume><issue>14</issue><spage>1442</spage><epage>1458</epage><pages>1442-1458</pages><issn>1082-6076</issn><eissn>1520-572X</eissn><coden>JLCTFC</coden><abstract>The objective of this study was to determine nicotine and the nicotine related impurities, that is, cotinine, myosmine, anatabine, anabasine, and β-nicotyrine, in electronic cigarette cartridges, the liquid used to fill the cartridges, and from smoke generated using the electronic cigarette devices. An HPLC method was validated for the determination. Samples of nicotine containing products were purchased via the internet from NJOY, Smoking Everywhere, CIXI, and Johnson Creek. Electronic cigarette devices were purchased from NJOY, Smoking Everywhere, and CIXI. The results from the testing found that (1) the nicotine content labeling was not accurate with some manufacturers, (2) nicotine is present in the "smoke" from electronic cigarettes, and (3) nicotine related impurities contents in cartridges and refills were found to vary by electronic cigarette manufacturer.</abstract><cop>Colchester</cop><pub>Taylor &amp; Francis Group</pub><doi>10.1080/10826076.2011.572213</doi><tpages>17</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1082-6076
ispartof Journal of liquid chromatography & related technologies, 2011-08, Vol.34 (14), p.1442-1458
issn 1082-6076
1520-572X
language eng
recordid cdi_pascalfrancis_primary_24718993
source Taylor and Francis Science and Technology Collection
subjects anatabine
Biological and medical sciences
cigarette
cotinine
e-cigarette
Medical sciences
nicotine
smokeless
Tobacco, tobacco smoking
Toxicology
title ANALYSIS OF ELECTRONIC CIGARETTE CARTRIDGES, REFILL SOLUTIONS, AND SMOKE FOR NICOTINE AND NICOTINE RELATED IMPURITIES
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T02%3A09%3A55IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pasca&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=ANALYSIS%20OF%20ELECTRONIC%20CIGARETTE%20CARTRIDGES,%20REFILL%20SOLUTIONS,%20AND%20SMOKE%20FOR%20NICOTINE%20AND%20NICOTINE%20RELATED%20IMPURITIES&rft.jtitle=Journal%20of%20liquid%20chromatography%20&%20related%20technologies&rft.au=Trehy,%20Michael%20L.&rft.date=2011-08-15&rft.volume=34&rft.issue=14&rft.spage=1442&rft.epage=1458&rft.pages=1442-1458&rft.issn=1082-6076&rft.eissn=1520-572X&rft.coden=JLCTFC&rft_id=info:doi/10.1080/10826076.2011.572213&rft_dat=%3Cproquest_pasca%3E2726591711%3C/proquest_pasca%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c431t-c6294d2a89b2c34888b1968604bbdc685475569dbbfff2016b0552ebac8c82873%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1030721282&rft_id=info:pmid/&rfr_iscdi=true