Pediatric Multiple Sclerosis: What we know and where are we headed?

Multiple Sclerosis (MS), an autoimmune mediated disease of the central nervous system, has historically been considered a disease of young adulthood. However, there has been increasing recognition that the disease can occur in adolescence and even early childhood and recent years have witnessed a su...

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Bibliographic Details
Published in:Child neuropsychology 2013-01, Vol.19 (1), p.1-22
Main Authors: MacAllister, William S., Christodoulou, Christopher, Milazzo, Maria, Preston, Thomas E., Serafin, Dana, Krupp, Lauren B., Harder, Lana
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Brain - pathology
Child
Child clinical studies
Childhood
Fatigue
Humans
Magnetic Resonance Imaging - methods
Medical sciences
Multiple Sclerosis
Multiple Sclerosis - drug therapy
Multiple Sclerosis - pathology
Multiple Sclerosis - psychology
Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis
Neurology
Neuropsychological
Neuropsychological Tests
Organic mental disorders. Neuropsychology
Pediatrics - methods
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Treatment
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Summary:Multiple Sclerosis (MS), an autoimmune mediated disease of the central nervous system, has historically been considered a disease of young adulthood. However, there has been increasing recognition that the disease can occur in adolescence and even early childhood and recent years have witnessed a surge of studies documenting the clinical features of the disease as it pertains to this young population. The purpose of this article is to review the literature on MS in childhood and adolescence, including the clinical presentation of the disease in this group, neuropathology and pathogenesis, magnetic resonance imaging findings, as well as neuropsychological and psychosocial considerations.
ISSN:0929-7049
1744-4136
DOI:10.1080/09297049.2011.639758