Biological Activity of 6-Pentyl-2H-pyran-2-one and Its Analogs

The in vitro biological activities (antifungal, phytotoxic) for a group of fungal metabolites structurally related to 6-pentyl-2H-pyran-2-one have been determined. Six compounds were tested and showed a degree of phytotoxicity in one or more of the assays employed. From among the analogs tested, (R)...

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Bibliographic Details
Published in:Journal of agricultural and food chemistry 1997-07, Vol.45 (7), p.2774-2776
Main Authors: Parker, Stephen R, Cutler, Horace G, Jacyno, John M, Hill, Robert A
Format: Article
Language:English
Subjects:
AGENT PATHOGENE
Biological and medical sciences
Biotechnology
Chemical control
COLEOPTILE
COLEOPTILES
COLEOPTILOS
Control
CRECIMIENTO
CROISSANCE
ENFERMEDADES FUNGOSAS
FITOTOXICIDAD
FONGICIDE
Fundamental and applied biological sciences. Psychology
FUNGAL DISEASES
Fungal plant pathogens
FUNGICIDAS
FUNGICIDES
GERMINACION
GERMINATION
GROWTH
MALADIE FONGIQUE
METABOLITE
METABOLITES
METABOLITOS
ORGANISMOS PATOGENOS
Parasitic plants. Weeds
PATHOGENS
PESTICIDAL PROPERTIES
Phytopathology. Animal pests. Plant and forest protection
PHYTOTOXICITE
PHYTOTOXICITY
PROPIEDADES PLAGUICIDAS
PROPRIETE DES PESTICIDES
SECONDARY METABOLITES
SEED
SEMENCE
SEMILLAS
Weeds
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Description
Summary:The in vitro biological activities (antifungal, phytotoxic) for a group of fungal metabolites structurally related to 6-pentyl-2H-pyran-2-one have been determined. Six compounds were tested and showed a degree of phytotoxicity in one or more of the assays employed. From among the analogs tested, (R)-5,6-dihydro-6-pentyl-2H-pyran-2-one has been identified as the most active against Penicillium species. Keywords: Antifungal; phytotoxic; 6-alkyl-2H-pyran-2-one; 5-alkyl-2H-furan-2-one
ISSN:0021-8561
1520-5118
DOI:10.1021/jf960681a