Design and Fabrication of Integrated Multianalyte Sensing Platform With Magnetic Micro-Coils

With the recent trends in bio-sensing technology, more attention is being devoted to sensor integration. This paper reports the design and fabrication of magnetically assisted multianalyte sensing platform comprising magnetic micro-coils to trap magnetic beads on the surface of sensing electrodes; i...

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Bibliographic Details
Published in:Journal of microelectromechanical systems 2013-12, Vol.22 (6), p.1339-1346
Main Authors: Stateikina, Irina, Eissa, Shimaa, Zourob, Mohammed
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biosensors
Biotechnology
chemical and biological sensors
Coils
Electrodes
Exact sciences and technology
Fabrication
Fundamental and applied biological sciences. Psychology
Instruments, apparatus, components and techniques common to several branches of physics and astronomy
Integrated biosensor
Layout
magnetic coils
Magnetic separation
Mechanical instruments, equipment and techniques
Methods. Procedures. Technologies
Micromechanical devices and systems
Physics
Sensors
Surface treatment
Various methods and equipments
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Summary:With the recent trends in bio-sensing technology, more attention is being devoted to sensor integration. This paper reports the design and fabrication of magnetically assisted multianalyte sensing platform comprising magnetic micro-coils to trap magnetic beads on the surface of sensing electrodes; integrated sensing electrode array for multianalyte sensing; and the additional micro-coils for removing the unbounded magnetic beads from the sensing electrodes' surfaces. Prototype device was designed and successfully fabricated using customized fabrication flow. Device's individual components were tested to ensure repeatability and reproducibility. Sensing platform were additionally tested in order to prove the successful implementation of magnetically assisted manipulation of micro-beads. The results of these tests support the original concept and their summary is presented herein.
ISSN:1057-7157
1941-0158
DOI:10.1109/JMEMS.2013.2261976