Postnatal changes in cerebral blood flow velocity in term intra-uterine growth-restricted neonates

Background: Intra-uterine growth-restricted (IUGR) fetuses are prone to hypoxic changes in the brain and neurodevelopmental sequelae in later life. Chronic hypoxaemia may also lead to polycythaemia in the fetal and neonatal period. Aim: To evaluate venous haematocrit and cerebral blood flow velocity...

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Bibliographic Details
Published in:Paediatrics and international child health 2014-08, Vol.34 (3), p.189-193
Main Authors: Basu, Sriparna, Dewangan, Shashikant, Barman, Sandeep, Shukla, Ram Chandra, Kumar, Ashok
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Blood Flow Velocity
Brain - growth & development
Cardiovascular system
Cerebral Arteries - physiology
Cerebral blood flow velocity
Female
Fetal Growth Retardation
General aspects
Haematocrit
Humans
Infant, Newborn
Intra-uterine growth restriction
Investigative techniques, diagnostic techniques (general aspects)
Male
Medical sciences
Newborn
Prospective Studies
Transcranial colour Doppler ultrasound
Ultrasonic investigative techniques
Young Adult
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Summary:Background: Intra-uterine growth-restricted (IUGR) fetuses are prone to hypoxic changes in the brain and neurodevelopmental sequelae in later life. Chronic hypoxaemia may also lead to polycythaemia in the fetal and neonatal period. Aim: To evaluate venous haematocrit and cerebral blood flow velocity (CBFV) in term IUGR neonates in the immediate postnatal period. Methods: This was a prospective observational study of 54 clinically healthy term IUGR neonates as cases and 50 term, appropriate-for-gestational-age (AGA), healthy neonates as controls. IUGR was defined as birthweight
ISSN:2046-9047
2046-9055
DOI:10.1179/2046905514Y.0000000124