Enzymatic Hydrolysis of Alken- and Alkyn-3-ol Acetates in an Acetone-Water Solvent System: Effect of Unsaturation on the Enantioselectivity of Pseudomonas cepacia Lipase-catalyzed Hydrolysis

High enantioselectivity was observed for the Pseudomonas cepacia lipase-catalyzed hydrolysis of (E)-allylic acetate 1 and propargylic acetate 2 in an acetone-water solvent system, while (E)-homoallylic acetate 3 and homopropargylic acetate 4 gave poor enantioselectivity.

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Bibliographic Details
Published in:Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 1995-01, Vol.59 (3), p.549-551
Main Authors: Kamezawa, Makoto, Raku, Takao, Tachibana, Hojun, Ohtani, Takehiko, Naoshima, Yoshinobu
Format: Article
Language:English
Subjects:
Bioconversions. Hemisynthesis
Biological and medical sciences
Biotechnology
Fundamental and applied biological sciences. Psychology
Methods. Procedures. Technologies
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Description
Summary:High enantioselectivity was observed for the Pseudomonas cepacia lipase-catalyzed hydrolysis of (E)-allylic acetate 1 and propargylic acetate 2 in an acetone-water solvent system, while (E)-homoallylic acetate 3 and homopropargylic acetate 4 gave poor enantioselectivity.
ISSN:0916-8451
1347-6947
DOI:10.1271/bbb.59.549