IRRITABLE BOWEL SYNDROME

The irritable bowel syndrome (IBS) is a functional gastrointestinal disorder whose hallmark is abdominal pain or discomfort associated with a change in the consistency or frequency of stools. In the western world, 8% to 23% of adults have IBS and its socioeconomic cost is substantial. Research-gener...

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Bibliographic Details
Published in:Annual review of medicine 2001-01, Vol.52 (1), p.319-338
Main Authors: Ringel, Yehuda, Sperber, Ami D, Drossman, Douglas A
Format: Article
Language:English
Subjects:
Biological and medical sciences
biopsychosocial model
brain-gut axis
Colonic Diseases, Functional - diagnosis
Colonic Diseases, Functional - epidemiology
Colonic Diseases, Functional - etiology
Colonic Diseases, Functional - physiopathology
Colonic Diseases, Functional - psychology
Colonic Diseases, Functional - therapy
Dietary Fiber - administration & dosage
functional gastrointestinal disorders
Gastroenterology. Liver. Pancreas. Abdomen
Gastrointestinal Motility
Humans
Life Style
Medical sciences
Other diseases. Semiology
Parasympatholytics - therapeutic use
psychological factors
Psychotherapy
Psychotropic Drugs - therapeutic use
Rome criteria
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Summary:The irritable bowel syndrome (IBS) is a functional gastrointestinal disorder whose hallmark is abdominal pain or discomfort associated with a change in the consistency or frequency of stools. In the western world, 8% to 23% of adults have IBS and its socioeconomic cost is substantial. Research-generated insights have led to the understanding of IBS as a disorder of brain-gut regulation. The experience of symptoms derives from dysregulation of the bidirectional communication system between the gastrointestinal tract and the brain, mediated by neuroendocrine and immunological factors and modulated by psychosocial factors. The biopsychosocial model integrates the various physical and psychosocial factors that contribute to the patient's illness. This model and the recently revised symptom-based criteria (i.e. the "Rome II criteria") form the basis for establishing a comprehensive and effective approach for the diagnosis and management of the disorder.
ISSN:0066-4219
1545-326X
DOI:10.1146/annurev.med.52.1.319