Renal Cell Carcinoma and Malignant Phase Hypertension

Many cross-sectional and follow-up studies of large numbers of patients with hypertension have demonstrated an increased prevalence and mortality from renal cancer. We report the details of three patients with renal cell carcinoma from a series of 254 consecutive patients with malignant phase hypert...

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Bibliographic Details
Published in:Blood pressure 2001, Vol.10 (1), p.16-21
Main Authors: Wong, P. S. C., Lip, G. Y. H., Gearty, J. C., Arkell, D. G., Howie, A. J., Ferreira, M. A. S., Beevers, D. G.
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Biological and medical sciences
Carcinoma, Renal Cell - complications
Carcinoma, Renal Cell - epidemiology
England - epidemiology
Female
Humans
Hypertension, Malignant - complications
Hypertension, Malignant - epidemiology
Kidneys
Male
Malignant Hypertension Renal Carcinoma
Medical sciences
Middle Aged
Nephrology. Urinary tract diseases
Prevalence
Retrospective Studies
Tumors of the urinary system
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Summary:Many cross-sectional and follow-up studies of large numbers of patients with hypertension have demonstrated an increased prevalence and mortality from renal cancer. We report the details of three patients with renal cell carcinoma from a series of 254 consecutive patients with malignant phase hypertension, an excess over the expected number reported from several large published series with nonmalignant hypertension. In view of this excess we investigated the prevalence of hypertension in a series of 192 consecutive patients who presented with a diagnosis of renal cell carcinoma, in comparison with a local unselected population screening survey. Hypertension was found in 43% of the renal carcinoma patients and 20% of the local population, also a clear excess. The mechanism of the association between renal cancer and malignant and non-malignant hypertension is unclear.
ISSN:0803-7051
1651-1999
DOI:10.1080/080370501750183336