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The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway
Chand Khanna and colleagues describe the work of the Comparative Oncology Trials Consortium (COTC), which provides infrastructure and resources to integrate naturally occurring dog cancer models into the development of new human cancer drugs, devices, and imaging techniques.
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| Published in: | PLoS medicine 2009-10, Vol.6 (10), p.e1000161-e1000161 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c563t-e36de8f73063d304f592c17fb3df098f75ec1833b1bc03402ee1ad199ee94b243 |
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| cites | cdi_FETCH-LOGICAL-c563t-e36de8f73063d304f592c17fb3df098f75ec1833b1bc03402ee1ad199ee94b243 |
| container_end_page | e1000161 |
| container_issue | 10 |
| container_start_page | e1000161 |
| container_title | PLoS medicine |
| container_volume | 6 |
| creator | Gordon, Ira Paoloni, Melissa Mazcko, Christina Khanna, Chand |
| description | Chand Khanna and colleagues describe the work of the Comparative Oncology Trials Consortium (COTC), which provides infrastructure and resources to integrate naturally occurring dog cancer models into the development of new human cancer drugs, devices, and imaging techniques. |
| doi_str_mv | 10.1371/journal.pmed.1000161 |
| format | article |
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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited: Citation: Gordon I, Paoloni M, Mazcko C, Khanna C (2009) The Comparative Oncology Trials Consortium: Using Spontaneously Occurring Cancers in Dogs to Inform the Cancer Drug Development Pathway. 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| subjects | Alliances Animals Animals, Domestic Antineoplastic Agents - therapeutic use Biology Cancer therapies Clinical trials Clinical Trials as Topic - veterinary Clinical Trials, Phase I as Topic Design Dog Diseases - drug therapy Dogs Drug Screening Assays, Antitumor Health in Action Histology Humans Immune system Infrastructure Integrated approach Models, Animal Multicenter Studies as Topic - veterinary National Cancer Institute (U.S.) - organization & administration Neoplasms - drug therapy Neoplasms - veterinary Oncology Oncology/Oncology Agents Pharmaceutical industry Species Specificity Studies United States |
| title | The Comparative Oncology Trials Consortium: using spontaneously occurring cancers in dogs to inform the cancer drug development pathway |
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