Common coinfections of Giardia intestinalis and Helicobacter pylori in non-symptomatic Ugandan children

The protozoan parasite Giardia intestinalis and the pathogenic bacterium Helicobacter pylori are well known for their high prevalences in human hosts worldwide. The prevalence of both organisms is known to peak in densely populated, low resource settings and children are infected early in life. Diff...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2012-08, Vol.6 (8), p.e1780-e1780
Main Authors: Ankarklev, Johan, Hestvik, Elin, Lebbad, Marianne, Lindh, Johan, Kaddu-Mulindwa, Deogratias H, Andersson, Jan O, Tylleskär, Thorkild, Tumwine, James K, Svärd, Staffan G
Format: Article
Language:English
Subjects:
Asymptomatic Diseases
Care and treatment
Child
Child, Preschool
Children
Coinfection - epidemiology
Demographic aspects
Developing countries
Diagnosis
Drinking water
Feces - microbiology
Feces - parasitology
Female
Gastric cancer
Gene loci
Genotypes
Giardia lamblia - isolation & purification
Giardiasis
Giardiasis - complications
Giardiasis - epidemiology
Health aspects
Helicobacter infections
Helicobacter Infections - complications
Helicobacter Infections - epidemiology
Helicobacter pylori - isolation & purification
Humans
Infant
Infant, Newborn
Infections
LDCs
Male
Malnutrition
Medicine
Molecular Sequence Data
Parasites
Pathogens
Population density
Protozoa
Risk factors
Sequence Analysis, DNA
Tropical diseases
Uganda - epidemiology
Ulcers
Citations: Items that cite this one
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Description
Summary:The protozoan parasite Giardia intestinalis and the pathogenic bacterium Helicobacter pylori are well known for their high prevalences in human hosts worldwide. The prevalence of both organisms is known to peak in densely populated, low resource settings and children are infected early in life. Different Giardia genotypes/assemblages have been associated with different symptoms and H. pylori with induction of cancer. Despite this, not much data are available from sub-Saharan Africa with regards to the prevalence of different G. intestinalis assemblages and their potential association with H. pylori infections. Fecal samples from 427 apparently healthy children, 0-12 years of age, living in urban Kampala, Uganda were analyzed for the presence of H. pylori and G. intestinalis. G. intestinalis was found in 86 (20.1%) out of the children and children age 1
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0001780