Dengue in Thailand and Cambodia: an assessment of the degree of underrecognized disease burden based on reported cases

Disease incidence data are needed to guide decision-making for public health interventions. Although dengue is a reportable disease in Thailand and Cambodia, the degree that reported incidence underrecognizes true disease burden is unknown. We utilized dengue incidence calculated from laboratory-con...

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Bibliographic Details
Published in:PLoS neglected tropical diseases 2011-03, Vol.5 (3), p.e996-e996
Main Authors: Wichmann, Ole, Yoon, In-Kyu, Vong, Sirenda, Limkittikul, Kriengsak, Gibbons, Robert V, Mammen, Mammen P, Ly, Sowath, Buchy, Philippe, Sirivichayakul, Chukiat, Buathong, Rome, Huy, Rekol, Letson, G William, Sabchareon, Arunee
Format: Article
Language:English
Subjects:
Adolescent
Age
Cambodia - epidemiology
Child
Child, Preschool
Cohort analysis
Cohort Studies
Consortia
Decision making
Dengue - epidemiology
Dengue fever
Epidemics
Health promotion
Hospitalization
Humans
Incidence
Infant
Infectious diseases
Infectious Diseases/Epidemiology and Control of Infectious Diseases
Infectious Diseases/Neglected Tropical Diseases
Infectious Diseases/Tropical and Travel-Associated Diseases
Laboratories
Life Sciences
Microbiology and Parasitology
Pediatrics
Product development
Prospective Studies
Public domain
Public health
Public Health and Epidemiology/Epidemiology
Thailand - epidemiology
Trends
Tropical diseases
Vaccines
Vector-borne diseases
Virology
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Description
Summary:Disease incidence data are needed to guide decision-making for public health interventions. Although dengue is a reportable disease in Thailand and Cambodia, the degree that reported incidence underrecognizes true disease burden is unknown. We utilized dengue incidence calculated from laboratory-confirmed outpatient and inpatient cases in prospective cohort studies to estimate the magnitude of dengue underrecognition and to establish more accurate disease burden estimates for these countries. Cohort studies were conducted among children aged 58,000 children in Cambodia were estimated to be hospitalized due to dengue. Calculating MFs by comparing prospective cohort study data to locally-reported national surveillance data is one approach to more accurately assess disease burden. These data indicate that although dengue is regularly reported in many countries, national surveillance data significantly underrecognize the true burden of disease.
ISSN:1935-2735
1935-2727
1935-2735
DOI:10.1371/journal.pntd.0000996