Prevalence study of yaws in the Democratic Republic of Congo using the lot quality assurance sampling method

Until the 1970s the prevalence of non-venereal trepanomatosis, including yaws, was greatly reduced after worldwide mass treatment. In 2005, cases were again reported in the Democratic Republic of the Congo. We carried out a survey to estimate the village-level prevalence of yaws in the region of Equ...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2009-07, Vol.4 (7), p.e6338-e6338
Main Authors: Gerstl, Sibylle, Kiwila, Gédeon, Dhorda, Mehul, Lonlas, Sylvaine, Myatt, Mark, Ilunga, Benoît Kebela, Lemasson, Denis, Szumilin, Elisabeth, Guerin, Philippe J, Ferradini, Laurent
Format: Article
Language:English
Subjects:
Analysis
Bacterial infections
Confidence intervals
Democratic Republic of the Congo - epidemiology
Disease
Epidemiology
Equatorial regions
Evidence-Based Healthcare/Methods for Diagnostic and Therapeutic Studies
Health services
Hemagglutination
HIV
Human immunodeficiency virus
Humans
Infections
Infectious Diseases/Bacterial Infections
Infectious Diseases/Neglected Tropical Diseases
Infectious Diseases/Skin Infections
Lot Quality Assurance Sampling
Methods
Prevalence
Public health
Public Health and Epidemiology/Epidemiology
Public Health and Epidemiology/Health Policy
Public Health and Epidemiology/Infectious Diseases
Quality assurance
Quality Control
Reagin
Rural areas
Sampling
Sampling methods
Serological tests
Skin
Surveillance systems
Surveys
Syphilis
System effectiveness
Treponema
Treponema pallidum
Yaws
Yaws - epidemiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Until the 1970s the prevalence of non-venereal trepanomatosis, including yaws, was greatly reduced after worldwide mass treatment. In 2005, cases were again reported in the Democratic Republic of the Congo. We carried out a survey to estimate the village-level prevalence of yaws in the region of Equator in the north of the country in order to define appropriate strategies to effectively treat the affected population. We designed a community-based survey using the Lot Quality Assurance Sampling method to classify the prevalence of active yaws in 14 groups of villages (lots). The classification into high, moderate, or low yaws prevalence corresponded to World Health Organization prevalence thresholds for identifying appropriate operational treatment strategies. Active yaws cases were defined by suggestive clinical signs and positive rapid plasma reagin and Treponema pallidum hemagglutination serological tests. The overall prevalence in the study area was 4.7% (95% confidence interval: 3.4-6.0). Two of 14 lots had high prevalence (>10%), three moderate prevalence (5-10%) and nine low prevalence (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0006338