Laryngeal reinnervation using ansa cervicalis for thyroid surgery-related unilateral vocal fold paralysis: a long-term outcome analysis of 237 cases

To evaluate the long-term efficacy of delayed laryngeal reinnervation using the main branch of the ansa cervicalis in treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery. UVFP remains a serious complication of thyroid surgery. Up to now, a completely satisfactory surgical t...

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Bibliographic Details
Published in:PloS one 2011-04, Vol.6 (4), p.e19128-e19128
Main Authors: Wang, Wei, Chen, Donghui, Chen, Shicai, Li, Ding, Li, Meng, Xia, Siwen, Zheng, Hongliang
Format: Article
Language:English
Subjects:
Acoustic properties
Adolescent
Adult
Analysis
Anastomosis
Biology
Care and treatment
Electromyography
Female
Group theory
Hospitals
Humans
Larynx - physiopathology
Larynx - surgery
Male
Medicine
Middle Aged
Nervous system
Observer Variation
Otolaryngology
Paralysis
Paralysis - surgery
Patients
Phonation
Physiological aspects
Postoperative Complications
Random Allocation
Recurrent Laryngeal Nerve - pathology
Reinnervation
Surgeons
Surgery
Thyroid
Thyroid gland
Treatment Outcome
Vocal Cord Paralysis - surgery
Vocal Cords - physiopathology
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Summary:To evaluate the long-term efficacy of delayed laryngeal reinnervation using the main branch of the ansa cervicalis in treatment of unilateral vocal fold paralysis (UVFP) caused by thyroid surgery. UVFP remains a serious complication of thyroid surgery. Up to now, a completely satisfactory surgical treatment of UVFP has been elusive. From Jan. 1996 to Jan. 2008, a total of 237 UVFP patients who underwent ansa cervicalis main branch-to-recurrent laryngeal nerve (RLN) anastomosis were enrolled as UVFP group; another 237 age- and gender-matched normal subjects served as control group. Videostroboscopy, vocal function assessment (acoustic analysis, perceptual evaluation and maximum phonation time), and electromyography were performed preoperatively and postoperatively. The mean follow-up period was 5.2±2.7 years, ranging from 2 to 12 years. Analysis of videostroboscopic findings indicated that the glottic closure, vocal fold edge, vocal fold position, phase symmetry and regularity were significantly improved in the UVFP group (P
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0019128