Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies

A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models...

Full description

Saved in:
Bibliographic Details
Published in:PLoS biology 2012-01, Vol.10 (1), p.e1001244-e1001244
Main Authors: Russel, Daniel, Lasker, Keren, Webb, Ben, Velázquez-Muriel, Javier, Tjioe, Elina, Schneidman-Duhovny, Dina, Peterson, Bret, Sali, Andrej
Format: Article
Language:English
Subjects:
Accuracy
Biology
Computational Biology - methods
Experiments
Genetic aspects
Heat shock proteins
Humans
Macromolecular Substances - chemistry
Models, Molecular
Monte Carlo method
Nuclear magnetic resonance spectroscopy
Physiological aspects
Proteins
RNA polymerase
RNA Polymerase II - chemistry
Software
Structure
Studies
Technology application
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models.
ISSN:1545-7885
1544-9173
1545-7885
DOI:10.1371/journal.pbio.1001244