Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies

A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models...

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Published in:PLoS biology 2012-01, Vol.10 (1), p.e1001244-e1001244
Main Authors: Russel, Daniel, Lasker, Keren, Webb, Ben, Velázquez-Muriel, Javier, Tjioe, Elina, Schneidman-Duhovny, Dina, Peterson, Bret, Sali, Andrej
Format: Article
Language:English
Subjects:
Accuracy
Biology
Computational Biology - methods
Experiments
Humans
Macromolecular Substances - chemistry
Models, Molecular
RNA polymerase
RNA Polymerase II - chemistry
Software
Studies
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cited_by cdi_FETCH-LOGICAL-c591t-962d2e2aec96b6431a60cfed0a66a5cbde27f34081a505c252fea9b439843fd23
cites cdi_FETCH-LOGICAL-c591t-962d2e2aec96b6431a60cfed0a66a5cbde27f34081a505c252fea9b439843fd23
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container_title PLoS biology
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creator Russel, Daniel
Lasker, Keren
Webb, Ben
Velázquez-Muriel, Javier
Tjioe, Elina
Schneidman-Duhovny, Dina
Peterson, Bret
Sali, Andrej
description A set of software tools for building and distributing models of macromolecular assemblies uses an integrative structure modeling approach, which casts the building of models as a computational optimization problem where information is encoded into a scoring function used to evaluate candidate models.
doi_str_mv 10.1371/journal.pbio.1001244
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subjects Accuracy
Biology
Computational Biology - methods
Experiments
Humans
Macromolecular Substances - chemistry
Models, Molecular
RNA polymerase
RNA Polymerase II - chemistry
Software
Studies
title Putting the pieces together: integrative modeling platform software for structure determination of macromolecular assemblies
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