Analyzing and mapping sweat metabolomics by high-resolution NMR spectroscopy

The content of human sweat is studied by high-resolution NMR, and the majority of organic components most often found in sweat of conditionally healthy people are identified. Original and simple tools are designed for sweat sampling from different areas of human body. The minimal surface area needed...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2011-12, Vol.6 (12), p.e28824-e28824
Main Authors: Kutyshenko, Viktor P, Molchanov, Maxim, Beskaravayny, Peter, Uversky, Vladimir N, Timchenko, Maria A
Format: Article
Language:English
Subjects:
Adult
Amino acids
Biology
Biophysics
Biosynthesis
Chemistry
Child
Child, Preschool
Clinical medicine
Feet
Female
Glycerol
High resolution
Human body
Humans
Lactates
Lactic acid
Lipids
Magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy - methods
Male
Medicine
Metabolism
Metabolites
Metabolomics
Middle Aged
NMR
NMR spectroscopy
Nuclear magnetic resonance
Nuclear magnetic resonance spectroscopy
Proteins
Pyruvic acid
Sampling
Serine
Skin
Spectroscopy
Spectrum analysis
Surface area
Sweat
Sweat - metabolism
Urine
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The content of human sweat is studied by high-resolution NMR, and the majority of organic components most often found in sweat of conditionally healthy people are identified. Original and simple tools are designed for sweat sampling from different areas of human body. The minimal surface area needed for sampling is in the range of 50-100 cm(2). On all the surface parts of the human body examined in this work, the main constituents forming a sweat metabolic profile are lactate, glycerol, pyruvate, and serine. The only exception is the sole of the foot (planta pedis), where trace amounts of glycerol are found. An attempt is made to explain the presence of specified metabolites and their possible origin.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0028824