Renal function and risk factors of moderate to severe chronic kidney disease in Golestan Province, northeast of Iran

The incidence of end-stage renal disease is increasing worldwide. Earlier studies reported high prevalence rates of obesity and hypertension, two major risk factors of chronic kidney disease (CKD), in Golestan Province, Iran. We aimed to investigate prevalence of moderate to severe CKD and its risk...

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Bibliographic Details
Published in:PloS one 2010-12, Vol.5 (12), p.e14216-e14216
Main Authors: Najafi, Iraj, Attari, Fatemeh, Islami, Farhad, Shakeri, Ramin, Malekzadeh, Fatemeh, Salahi, Rasool, Gharavi, Mina Yapan, Hosseini, Mostafa, Broumand, Behrooz, Haghighi, Ali Nobakht, Larijani, Bagher, Malekzadeh, Reza
Format: Article
Language:English
Subjects:
Aged
Aging
Body mass
Body Mass Index
Body size
Body weight
Cancer
Chronic kidney failure
Comorbidity
Confidence intervals
Coronary artery disease
Creatinine
Developing countries
Diabetes
Diabetes mellitus
End-stage renal disease
Endocrinology
Epidemiology
Female
Glomerular Filtration Rate
Health risk assessment
Health risks
Health screening
Health surveillance
Heart
Heart diseases
Hospitals
Humans
Hypertension
Inhabitants
Insulin resistance
Iran
Ischemia
Kidney - physiology
Kidney diseases
Kidney Failure, Chronic - diagnosis
Kidney Failure, Chronic - ethnology
Kidney Failure, Chronic - physiopathology
LDCs
Male
Medical diagnosis
Medical research
Middle Aged
Myocardial infarction
Nephrology
Nephrology/Chronic Kidney Disease
Obesity
Overweight
Population
Prevalence
Prevalence studies (Epidemiology)
Public health
Public Health and Epidemiology/Epidemiology
Public Health and Epidemiology/Health Policy
Renal function
Risk analysis
Risk Factors
Screening
Studies
Surveys and Questionnaires
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Summary:The incidence of end-stage renal disease is increasing worldwide. Earlier studies reported high prevalence rates of obesity and hypertension, two major risk factors of chronic kidney disease (CKD), in Golestan Province, Iran. We aimed to investigate prevalence of moderate to severe CKD and its risk factors in the region. Questionnaire data and blood samples were collected from 3591 participants (≥18 years old) from the general population. Based on serum creatinine levels, glomerular filtration rate (GFR) was estimated. High body mass index (BMI) was common: 35.0% of participants were overweight (BMI 25-29.9) and 24.5% were obese (BMI ≥30). Prevalence of CKD stages 3 to 5 (CKD-S3-5), i.e., GFR
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0014216