Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa

Pneumonia is a leading cause of death in children worldwide. A simple clinical score predicting the probability of death in a young child with lower respiratory tract infection (LRTI) could aid clinicians in case management and provide a standardized severity measure during epidemiologic studies. We...

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Bibliographic Details
Published in:PloS one 2012-01, Vol.7 (1), p.e27793-e27793
Main Authors: Reed, Carrie, Madhi, Shabir A, Klugman, Keith P, Kuwanda, Locadiah, Ortiz, Justin R, Finelli, Lyn, Fry, Alicia M
Format: Article
Language:English
Subjects:
Age
AIDS vaccines
Analysis
Calibration
Case management
Children
Children & youth
Clinical medicine
Councils
Death
Disease control
Disease prevention
Epidemiology
Fatalities
Female
Goodness of fit
Health risks
HIV
HIV Infections - complications
HIV Infections - epidemiology
Hospitalization
Hospitalization - statistics & numerical data
Hospitals
Human immunodeficiency virus
Humans
Illnesses
Immunization
Infant
Infant, Newborn
Infection
Infections
Influenza
Lung diseases
Male
Medical research
Medicine
Mortality
Oxygen
Oxygen content
Pathogens
Pediatrics
Placebos
Pneumococcal Infections - epidemiology
Pneumococcal Infections - prevention & control
Pneumonia
Prognosis
Public health
Randomized Controlled Trials as Topic
Regression analysis
Regression models
Resampling
Research Design
Respiratory diseases
Respiratory Function Tests - methods
Respiratory tract
Respiratory tract diseases
Respiratory tract infection
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - epidemiology
Risk analysis
Risk factors
Saturation
Severity of Illness Index
South Africa - epidemiology
Statistical analysis
Systematic review
Vaccination
Wheezing
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Description
Summary:Pneumonia is a leading cause of death in children worldwide. A simple clinical score predicting the probability of death in a young child with lower respiratory tract infection (LRTI) could aid clinicians in case management and provide a standardized severity measure during epidemiologic studies. We analyzed 4,148 LRTI hospitalizations in children
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0027793