The ArcB leucine zipper domain is required for proper ArcB signaling

The Arc two-component system modulates the expression of numerous genes in response to respiratory growth conditions. This system comprises ArcA as the response regulator and ArcB as the sensor kinase. ArcB is a tripartite histidine kinase whose activity is regulated by the oxidation of two cytosol-...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2012-05, Vol.7 (5), p.e38187
Main Authors: Nuñez Oreza, Luis Alberto, Alvarez, Adrián F, Arias-Olguín, Imilla I, Torres Larios, Alfredo, Georgellis, Dimitris
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Analysis
ArcB protein
Automation
Biology
Chemical bonds
Coils
Cysteine
Cytosol
DNA binding proteins
E coli
Escherichia coli
Escherichia coli - enzymology
Escherichia coli Proteins - chemistry
Escherichia coli Proteins - genetics
Escherichia coli Proteins - metabolism
Gene expression
Growth conditions
Histidine
Histidine kinase
Kinases
Laboratories
Leucine
Leucine zipper proteins
Leucine Zippers
Membrane Proteins - chemistry
Membrane Proteins - genetics
Membrane Proteins - metabolism
Metabolism
Metabolites
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Oxidation
Phosphoric Monoester Hydrolases - metabolism
Protein Kinases - chemistry
Protein Kinases - genetics
Protein Kinases - metabolism
Proteins
Residues
Sensors
Sequence Analysis
Signaling
Transmitters
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333
cites cdi_FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333
container_end_page
container_issue 5
container_start_page e38187
container_title PloS one
container_volume 7
creator Nuñez Oreza, Luis Alberto
Alvarez, Adrián F
Arias-Olguín, Imilla I
Torres Larios, Alfredo
Georgellis, Dimitris
description The Arc two-component system modulates the expression of numerous genes in response to respiratory growth conditions. This system comprises ArcA as the response regulator and ArcB as the sensor kinase. ArcB is a tripartite histidine kinase whose activity is regulated by the oxidation of two cytosol-located redox-active cysteine residues that participate in intermolecular disulfide bond formation. Here, we report that the ArcB protein segment covering residues 70-121, fulfills the molecular characteristics of a leucine zipper containing coiled coil structure. Also, mutational analyses of this segment reveal three different phenotypical effects to be distributed along the coiled coil structure of ArcB, demonstrating that this motif is essential for proper ArcB signaling.
doi_str_mv 10.1371/journal.pone.0038187
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1325018102</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A476993796</galeid><doaj_id>oai_doaj_org_article_42369ed3bc0f4e939787f25dba4c84e3</doaj_id><sourcerecordid>A476993796</sourcerecordid><originalsourceid>FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333</originalsourceid><addsrcrecordid>eNqNkl2L1DAUhoso7rr6D0QLguDFjPlo83GzMK5fAwsLunobMslpJ0PbdJNW1F9vZqe7TEFBcpFw8rzvORzeLHuO0RJTjt_u_Bg63Sx738ESISqw4A-yUywpWTCC6MOj90n2JMYdQiUVjD3OTghhjBVcnmbvr7eQr4J5lzcwGtdB_tv1PYTc-la7LncxD3AzugA2r3zI--D3v7eK6Oo0gOvqp9mjSjcRnk33Wfbt44fri8-Ly6tP64vV5cJwIYcF11gUTCJealIKK6CyhoMhjOBKciG4ZQaIKCxYUZR4Y1BBuQHDSi6lppSeZS8Pvn3jo5oWEBWmpERYYEQSsT4Q1uud6oNrdfilvHbqtuBDrXQYnGlAFYQyCZamNlUBkqYJeEVKu9GFEQXsu51P3cZNC9ZANwTdzEznP53bqtr_UJSyZI6TwavJIPibEeLwj5EnqtZpKtdVPpmZ1kWjVgVnUlIuWaKWf6HSsdA6kyJQuVSfCd7MBIkZ4OdQ6zFGtf765f_Zq-9z9vURuwXdDNvom3FwvotzsDiAJvgYA1T3m8NI7RN8tw21T7CaEpxkL463fi-6iyz9A6uG6jY</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1325018102</pqid></control><display><type>article</type><title>The ArcB leucine zipper domain is required for proper ArcB signaling</title><source>Publicly Available Content Database</source><source>PubMed Central(OpenAccess)</source><creator>Nuñez Oreza, Luis Alberto ; Alvarez, Adrián F ; Arias-Olguín, Imilla I ; Torres Larios, Alfredo ; Georgellis, Dimitris</creator><contributor>Bravo, Alejandra</contributor><creatorcontrib>Nuñez Oreza, Luis Alberto ; Alvarez, Adrián F ; Arias-Olguín, Imilla I ; Torres Larios, Alfredo ; Georgellis, Dimitris ; Bravo, Alejandra</creatorcontrib><description>The Arc two-component system modulates the expression of numerous genes in response to respiratory growth conditions. This system comprises ArcA as the response regulator and ArcB as the sensor kinase. ArcB is a tripartite histidine kinase whose activity is regulated by the oxidation of two cytosol-located redox-active cysteine residues that participate in intermolecular disulfide bond formation. Here, we report that the ArcB protein segment covering residues 70-121, fulfills the molecular characteristics of a leucine zipper containing coiled coil structure. Also, mutational analyses of this segment reveal three different phenotypical effects to be distributed along the coiled coil structure of ArcB, demonstrating that this motif is essential for proper ArcB signaling.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0038187</identifier><identifier>PMID: 22666479</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Amino Acid Sequence ; Analysis ; ArcB protein ; Automation ; Biology ; Chemical bonds ; Coils ; Cysteine ; Cytosol ; DNA binding proteins ; E coli ; Escherichia coli ; Escherichia coli - enzymology ; Escherichia coli Proteins - chemistry ; Escherichia coli Proteins - genetics ; Escherichia coli Proteins - metabolism ; Gene expression ; Growth conditions ; Histidine ; Histidine kinase ; Kinases ; Laboratories ; Leucine ; Leucine zipper proteins ; Leucine Zippers ; Membrane Proteins - chemistry ; Membrane Proteins - genetics ; Membrane Proteins - metabolism ; Metabolism ; Metabolites ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Mutation ; Oxidation ; Phosphoric Monoester Hydrolases - metabolism ; Protein Kinases - chemistry ; Protein Kinases - genetics ; Protein Kinases - metabolism ; Proteins ; Residues ; Sensors ; Sequence Analysis ; Signaling ; Transmitters</subject><ispartof>PloS one, 2012-05, Vol.7 (5), p.e38187</ispartof><rights>COPYRIGHT 2012 Public Library of Science</rights><rights>2012 Nuñez Oreza et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Nuñez Oreza et al. 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333</citedby><cites>FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1325018102/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1325018102?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22666479$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Bravo, Alejandra</contributor><creatorcontrib>Nuñez Oreza, Luis Alberto</creatorcontrib><creatorcontrib>Alvarez, Adrián F</creatorcontrib><creatorcontrib>Arias-Olguín, Imilla I</creatorcontrib><creatorcontrib>Torres Larios, Alfredo</creatorcontrib><creatorcontrib>Georgellis, Dimitris</creatorcontrib><title>The ArcB leucine zipper domain is required for proper ArcB signaling</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>The Arc two-component system modulates the expression of numerous genes in response to respiratory growth conditions. This system comprises ArcA as the response regulator and ArcB as the sensor kinase. ArcB is a tripartite histidine kinase whose activity is regulated by the oxidation of two cytosol-located redox-active cysteine residues that participate in intermolecular disulfide bond formation. Here, we report that the ArcB protein segment covering residues 70-121, fulfills the molecular characteristics of a leucine zipper containing coiled coil structure. Also, mutational analyses of this segment reveal three different phenotypical effects to be distributed along the coiled coil structure of ArcB, demonstrating that this motif is essential for proper ArcB signaling.</description><subject>Amino Acid Sequence</subject><subject>Analysis</subject><subject>ArcB protein</subject><subject>Automation</subject><subject>Biology</subject><subject>Chemical bonds</subject><subject>Coils</subject><subject>Cysteine</subject><subject>Cytosol</subject><subject>DNA binding proteins</subject><subject>E coli</subject><subject>Escherichia coli</subject><subject>Escherichia coli - enzymology</subject><subject>Escherichia coli Proteins - chemistry</subject><subject>Escherichia coli Proteins - genetics</subject><subject>Escherichia coli Proteins - metabolism</subject><subject>Gene expression</subject><subject>Growth conditions</subject><subject>Histidine</subject><subject>Histidine kinase</subject><subject>Kinases</subject><subject>Laboratories</subject><subject>Leucine</subject><subject>Leucine zipper proteins</subject><subject>Leucine Zippers</subject><subject>Membrane Proteins - chemistry</subject><subject>Membrane Proteins - genetics</subject><subject>Membrane Proteins - metabolism</subject><subject>Metabolism</subject><subject>Metabolites</subject><subject>Models, Molecular</subject><subject>Molecular Sequence Data</subject><subject>Mutagenesis, Site-Directed</subject><subject>Mutation</subject><subject>Oxidation</subject><subject>Phosphoric Monoester Hydrolases - metabolism</subject><subject>Protein Kinases - chemistry</subject><subject>Protein Kinases - genetics</subject><subject>Protein Kinases - metabolism</subject><subject>Proteins</subject><subject>Residues</subject><subject>Sensors</subject><subject>Sequence Analysis</subject><subject>Signaling</subject><subject>Transmitters</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNkl2L1DAUhoso7rr6D0QLguDFjPlo83GzMK5fAwsLunobMslpJ0PbdJNW1F9vZqe7TEFBcpFw8rzvORzeLHuO0RJTjt_u_Bg63Sx738ESISqw4A-yUywpWTCC6MOj90n2JMYdQiUVjD3OTghhjBVcnmbvr7eQr4J5lzcwGtdB_tv1PYTc-la7LncxD3AzugA2r3zI--D3v7eK6Oo0gOvqp9mjSjcRnk33Wfbt44fri8-Ly6tP64vV5cJwIYcF11gUTCJealIKK6CyhoMhjOBKciG4ZQaIKCxYUZR4Y1BBuQHDSi6lppSeZS8Pvn3jo5oWEBWmpERYYEQSsT4Q1uud6oNrdfilvHbqtuBDrXQYnGlAFYQyCZamNlUBkqYJeEVKu9GFEQXsu51P3cZNC9ZANwTdzEznP53bqtr_UJSyZI6TwavJIPibEeLwj5EnqtZpKtdVPpmZ1kWjVgVnUlIuWaKWf6HSsdA6kyJQuVSfCd7MBIkZ4OdQ6zFGtf765f_Zq-9z9vURuwXdDNvom3FwvotzsDiAJvgYA1T3m8NI7RN8tw21T7CaEpxkL463fi-6iyz9A6uG6jY</recordid><startdate>20120530</startdate><enddate>20120530</enddate><creator>Nuñez Oreza, Luis Alberto</creator><creator>Alvarez, Adrián F</creator><creator>Arias-Olguín, Imilla I</creator><creator>Torres Larios, Alfredo</creator><creator>Georgellis, Dimitris</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20120530</creationdate><title>The ArcB leucine zipper domain is required for proper ArcB signaling</title><author>Nuñez Oreza, Luis Alberto ; Alvarez, Adrián F ; Arias-Olguín, Imilla I ; Torres Larios, Alfredo ; Georgellis, Dimitris</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Amino Acid Sequence</topic><topic>Analysis</topic><topic>ArcB protein</topic><topic>Automation</topic><topic>Biology</topic><topic>Chemical bonds</topic><topic>Coils</topic><topic>Cysteine</topic><topic>Cytosol</topic><topic>DNA binding proteins</topic><topic>E coli</topic><topic>Escherichia coli</topic><topic>Escherichia coli - enzymology</topic><topic>Escherichia coli Proteins - chemistry</topic><topic>Escherichia coli Proteins - genetics</topic><topic>Escherichia coli Proteins - metabolism</topic><topic>Gene expression</topic><topic>Growth conditions</topic><topic>Histidine</topic><topic>Histidine kinase</topic><topic>Kinases</topic><topic>Laboratories</topic><topic>Leucine</topic><topic>Leucine zipper proteins</topic><topic>Leucine Zippers</topic><topic>Membrane Proteins - chemistry</topic><topic>Membrane Proteins - genetics</topic><topic>Membrane Proteins - metabolism</topic><topic>Metabolism</topic><topic>Metabolites</topic><topic>Models, Molecular</topic><topic>Molecular Sequence Data</topic><topic>Mutagenesis, Site-Directed</topic><topic>Mutation</topic><topic>Oxidation</topic><topic>Phosphoric Monoester Hydrolases - metabolism</topic><topic>Protein Kinases - chemistry</topic><topic>Protein Kinases - genetics</topic><topic>Protein Kinases - metabolism</topic><topic>Proteins</topic><topic>Residues</topic><topic>Sensors</topic><topic>Sequence Analysis</topic><topic>Signaling</topic><topic>Transmitters</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nuñez Oreza, Luis Alberto</creatorcontrib><creatorcontrib>Alvarez, Adrián F</creatorcontrib><creatorcontrib>Arias-Olguín, Imilla I</creatorcontrib><creatorcontrib>Torres Larios, Alfredo</creatorcontrib><creatorcontrib>Georgellis, Dimitris</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: Opposing Viewpoints</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Nursing &amp; Allied Health Database</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies &amp; Aerospace Collection</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Materials Science Database</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Meteorological &amp; Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>ProQuest Biological Science Collection</collection><collection>Agriculture Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Engineering Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest advanced technologies &amp; aerospace journals</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials science collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals(OpenAccess)</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nuñez Oreza, Luis Alberto</au><au>Alvarez, Adrián F</au><au>Arias-Olguín, Imilla I</au><au>Torres Larios, Alfredo</au><au>Georgellis, Dimitris</au><au>Bravo, Alejandra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The ArcB leucine zipper domain is required for proper ArcB signaling</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2012-05-30</date><risdate>2012</risdate><volume>7</volume><issue>5</issue><spage>e38187</spage><pages>e38187-</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>The Arc two-component system modulates the expression of numerous genes in response to respiratory growth conditions. This system comprises ArcA as the response regulator and ArcB as the sensor kinase. ArcB is a tripartite histidine kinase whose activity is regulated by the oxidation of two cytosol-located redox-active cysteine residues that participate in intermolecular disulfide bond formation. Here, we report that the ArcB protein segment covering residues 70-121, fulfills the molecular characteristics of a leucine zipper containing coiled coil structure. Also, mutational analyses of this segment reveal three different phenotypical effects to be distributed along the coiled coil structure of ArcB, demonstrating that this motif is essential for proper ArcB signaling.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>22666479</pmid><doi>10.1371/journal.pone.0038187</doi><tpages>e38187</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1932-6203
ispartof PloS one, 2012-05, Vol.7 (5), p.e38187
issn 1932-6203
1932-6203
language eng
recordid cdi_plos_journals_1325018102
source Publicly Available Content Database; PubMed Central(OpenAccess)
subjects Amino Acid Sequence
Analysis
ArcB protein
Automation
Biology
Chemical bonds
Coils
Cysteine
Cytosol
DNA binding proteins
E coli
Escherichia coli
Escherichia coli - enzymology
Escherichia coli Proteins - chemistry
Escherichia coli Proteins - genetics
Escherichia coli Proteins - metabolism
Gene expression
Growth conditions
Histidine
Histidine kinase
Kinases
Laboratories
Leucine
Leucine zipper proteins
Leucine Zippers
Membrane Proteins - chemistry
Membrane Proteins - genetics
Membrane Proteins - metabolism
Metabolism
Metabolites
Models, Molecular
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Oxidation
Phosphoric Monoester Hydrolases - metabolism
Protein Kinases - chemistry
Protein Kinases - genetics
Protein Kinases - metabolism
Proteins
Residues
Sensors
Sequence Analysis
Signaling
Transmitters
title The ArcB leucine zipper domain is required for proper ArcB signaling
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T04%3A15%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20ArcB%20leucine%20zipper%20domain%20is%20required%20for%20proper%20ArcB%20signaling&rft.jtitle=PloS%20one&rft.au=Nu%C3%B1ez%20Oreza,%20Luis%20Alberto&rft.date=2012-05-30&rft.volume=7&rft.issue=5&rft.spage=e38187&rft.pages=e38187-&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0038187&rft_dat=%3Cgale_plos_%3EA476993796%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c789t-7a18469075a258d8efdc7ec2621f97887d6ce284ded8451bc0437cec65799a333%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1325018102&rft_id=info:pmid/22666479&rft_galeid=A476993796&rfr_iscdi=true