Health-related quality of life in long-term survivors of relapsed childhood acute lymphoblastic leukemia

Relapses occur in about 20% of children with acute lymphoblastic leukemia (ALL). Approximately one-third of these children can be cured. Their risk for late effects is high because of intensified treatment, but their health-related quality of life (HRQOL) was largely unmeasured. Our aim was to compa...

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Bibliographic Details
Published in:PloS one 2012-05, Vol.7 (5), p.e38015-e38015
Main Authors: Essig, Stefan, von der Weid, Nicolas X, Strippoli, Marie-Pierre F, Rebholz, Cornelia E, Michel, Gisela, Rueegg, Corina S, Niggli, Felix K, Kuehni, Claudia E
Format: Article
Language:English
Subjects:
Acute lymphatic leukemia
Acute lymphoblastic leukemia
Acute lymphocytic leukemia
Adolescent
Analysis
Cancer
Cancer therapies
Child
Child, Preschool
Childhood
Children
Data processing
Ethics
Female
Health
Health risk assessment
Health screening
Humans
Infant
Infant, Newborn
Leukemia
Lymphatic leukemia
Male
Medical diagnosis
Medicine
Mental health
Nervous system
Norms
Oncology
Pediatrics
Population
Precursor Cell Lymphoblastic Leukemia-Lymphoma - psychology
Preventive medicine
Quality of Life
Quantitative psychology
Questionnaires
Recurrence
Recurrence (Disease)
Stem cell transplantation
Studies
Surveys
Surveys and Questionnaires
Survivors - psychology
Switzerland
Tumors
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Summary:Relapses occur in about 20% of children with acute lymphoblastic leukemia (ALL). Approximately one-third of these children can be cured. Their risk for late effects is high because of intensified treatment, but their health-related quality of life (HRQOL) was largely unmeasured. Our aim was to compare HRQOL of ALL survivors with the general population, and of relapsed with non-relapsed ALL survivors. As part of the Swiss Childhood Cancer Survivor Study (SCCSS) we sent a questionnaire to all ALL survivors in Switzerland who had been diagnosed between 1976-2003 at age
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0038015