A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia

Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the S...

Full description

Saved in:
Bibliographic Details
Published in:PloS one 2012-10, Vol.7 (10), p.e46586-e46586
Main Authors: Serranová, Tereza, Jech, Robert, Martí, Maria José, Modreanu, Raluca, Valldeoriola, Francesc, Sieger, Tomáš, Růžička, Evžen, Valls-Solé, Josep
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Adult
Aged
Analysis
Auditory defects
Biology
Brain research
Care and treatment
Case-Control Studies
Clinical trials
Dystonia
Electrical stimuli
Electromyography
Female
Head Movements
Humans
Kinematics
Latency
Loudness Perception
Male
Medicine
Middle Aged
Motor neurons
Motor task performance
Movement disorders
Muscles
Músculs
Neck
Neurologia
Neurology
Neurosciences
Parkinson's disease
Patients
Perception
Psychomotor Performance
Reaction Time
Reaction time task
Synchronism
Synchronization
Test procedures
Torticollis - physiopathology
Trastorns motors
Variance analysis
Young Adult
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c599t-8fae201802b20a53c7227d936db59fee20165e36a067c29515cf5e716997e2293
cites
container_end_page e46586
container_issue 10
container_start_page e46586
container_title PloS one
container_volume 7
creator Serranová, Tereza
Jech, Robert
Martí, Maria José
Modreanu, Raluca
Valldeoriola, Francesc
Sieger, Tomáš
Růžička, Evžen
Valls-Solé, Josep
description Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the StartReact method. In this test, a startling auditory stimulus (SAS) is delivered unexpectedly at the time of the imperative signal (IS) in a reaction time task to cause a faster execution of the prepared motor programme. We expected that CD patients would show an abnormal StartReact phenomenon. Fifteen CD patients and 15 age matched control subjects (CS) were asked to perform a rotational movement (RM) to either side as quick as possible immediately after IS perception (a low intensity electrical stimulus to the II finger). In randomly interspersed test trials (25%) a 130 dB SAS was delivered simultaneously with the IS. We recorded RMs in the horizontal plane with a high speed video camera (2.38 ms per frame) in synchronization with the IS. The RM kinematic-parameters (latency, velocity, duration and amplitude) were analyzed using video-editing software and screen protractor. Patients were asked to rate the difficulty of their RMs in a numerical rating scale. In control trials, CD patients executed slower RMs (repeated measures ANOVA, p
doi_str_mv 10.1371/journal.pone.0046586
format article
fullrecord <record><control><sourceid>gale_plos_</sourceid><recordid>TN_cdi_plos_journals_1326560305</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A498258324</galeid><doaj_id>oai_doaj_org_article_03f6b6b710cf42748f21dd1a3d726761</doaj_id><sourcerecordid>A498258324</sourcerecordid><originalsourceid>FETCH-LOGICAL-c599t-8fae201802b20a53c7227d936db59fee20165e36a067c29515cf5e716997e2293</originalsourceid><addsrcrecordid>eNptUstqGzEUFaWlSd3-QWkHCqUbu3qMpNEmYEIfgUA3zVrIksaW0YxcPQz5-2riiUlKF0LSvece6Zx7AXiP4AoRjr7uQ4mj8qtDGO0KwpbRjr0Al0gQvGQYkpdPzhfgTUp7CCnpGHsNLjCBAlHRXYK7deNDMY0qxuUQ75uU3VB8SU042qjDYFNzDL6MWdXkUIODHXPj3eCyyi6MjRsbbePRaeUbc59yGJ16C171yif7bt4X4O77t9_XP5e3v37cXK9vl5oKkZddryyGqIN4g6GiRHOMuRGEmQ0VvZ1yjFrCFGRcY0ER1T21HDEhuMVYkAX4eOI9-JDk7EiSiGBGGSRV7wLcnBAmqL08RDdUHTIoJx8CIW6litlpbyUkPduwDUdQ9y3mbddjZAxSxHDMOEOV62p-rWwGa3Q1Iir_jPR5ZnQ7uQ1HSVo-_aUSoBOBTkXLaKtvWuWHwvNlWhhyLAnBHYe15sv8aAx_ik1ZDi5p670abShVK0KtoLClvEI__QP9vyOfT6itqqJ3Vvm8S7XDUzOTXLeiw7QjuK3Adv5tDClF25-VIiinEXykl9MIynkEa9mHpy6dix5njvwFbzHZCA</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1326560305</pqid></control><display><type>article</type><title>A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia</title><source>Publicly Available Content (ProQuest)</source><source>PubMed Central</source><creator>Serranová, Tereza ; Jech, Robert ; Martí, Maria José ; Modreanu, Raluca ; Valldeoriola, Francesc ; Sieger, Tomáš ; Růžička, Evžen ; Valls-Solé, Josep</creator><creatorcontrib>Serranová, Tereza ; Jech, Robert ; Martí, Maria José ; Modreanu, Raluca ; Valldeoriola, Francesc ; Sieger, Tomáš ; Růžička, Evžen ; Valls-Solé, Josep</creatorcontrib><description>Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the StartReact method. In this test, a startling auditory stimulus (SAS) is delivered unexpectedly at the time of the imperative signal (IS) in a reaction time task to cause a faster execution of the prepared motor programme. We expected that CD patients would show an abnormal StartReact phenomenon. Fifteen CD patients and 15 age matched control subjects (CS) were asked to perform a rotational movement (RM) to either side as quick as possible immediately after IS perception (a low intensity electrical stimulus to the II finger). In randomly interspersed test trials (25%) a 130 dB SAS was delivered simultaneously with the IS. We recorded RMs in the horizontal plane with a high speed video camera (2.38 ms per frame) in synchronization with the IS. The RM kinematic-parameters (latency, velocity, duration and amplitude) were analyzed using video-editing software and screen protractor. Patients were asked to rate the difficulty of their RMs in a numerical rating scale. In control trials, CD patients executed slower RMs (repeated measures ANOVA, p&lt;0.10(-5)), and reached a smaller final head position angle relative to the midline (p&lt;0.05), than CS. In test trials, SAS improved all RMs in both groups (p&lt;0.10(-14)). In addition, patients were more likely to reach beyond their baseline RM than CS (χ(2), p&lt;0.001) and rated their performance better than in control trials (t-test, p&lt;0.01). We found improvement of kinematic parameters and subjective perception of motor performance in CD patients with StartReact testing. Our results suggest that CD patients reach an adequate level of motor preparation before task execution.</description><identifier>ISSN: 1932-6203</identifier><identifier>EISSN: 1932-6203</identifier><identifier>DOI: 10.1371/journal.pone.0046586</identifier><identifier>PMID: 23091598</identifier><language>eng</language><publisher>United States: Public Library of Science</publisher><subject>Acoustic Stimulation ; Adult ; Aged ; Analysis ; Auditory defects ; Biology ; Brain research ; Care and treatment ; Case-Control Studies ; Clinical trials ; Dystonia ; Electrical stimuli ; Electromyography ; Female ; Head Movements ; Humans ; Kinematics ; Latency ; Loudness Perception ; Male ; Medicine ; Middle Aged ; Motor neurons ; Motor task performance ; Movement disorders ; Muscles ; Músculs ; Neck ; Neurologia ; Neurology ; Neurosciences ; Parkinson's disease ; Patients ; Perception ; Psychomotor Performance ; Reaction Time ; Reaction time task ; Synchronism ; Synchronization ; Test procedures ; Torticollis - physiopathology ; Trastorns motors ; Variance analysis ; Young Adult</subject><ispartof>PloS one, 2012-10, Vol.7 (10), p.e46586-e46586</ispartof><rights>COPYRIGHT 2012 Public Library of Science</rights><rights>Serranová et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>cc-by (c) Serranová, Tereza et al., 2012 info:eu-repo/semantics/openAccess &lt;a href="http://creativecommons.org/licenses/by/3.0/es"&gt;http://creativecommons.org/licenses/by/3.0/es&lt;/a&gt;</rights><rights>2012 Serranová et al 2012 Serranová et al</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c599t-8fae201802b20a53c7227d936db59fee20165e36a067c29515cf5e716997e2293</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1326560305/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1326560305?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25730,27900,27901,36988,36989,44565,53765,53767,75095</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23091598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Serranová, Tereza</creatorcontrib><creatorcontrib>Jech, Robert</creatorcontrib><creatorcontrib>Martí, Maria José</creatorcontrib><creatorcontrib>Modreanu, Raluca</creatorcontrib><creatorcontrib>Valldeoriola, Francesc</creatorcontrib><creatorcontrib>Sieger, Tomáš</creatorcontrib><creatorcontrib>Růžička, Evžen</creatorcontrib><creatorcontrib>Valls-Solé, Josep</creatorcontrib><title>A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia</title><title>PloS one</title><addtitle>PLoS One</addtitle><description>Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the StartReact method. In this test, a startling auditory stimulus (SAS) is delivered unexpectedly at the time of the imperative signal (IS) in a reaction time task to cause a faster execution of the prepared motor programme. We expected that CD patients would show an abnormal StartReact phenomenon. Fifteen CD patients and 15 age matched control subjects (CS) were asked to perform a rotational movement (RM) to either side as quick as possible immediately after IS perception (a low intensity electrical stimulus to the II finger). In randomly interspersed test trials (25%) a 130 dB SAS was delivered simultaneously with the IS. We recorded RMs in the horizontal plane with a high speed video camera (2.38 ms per frame) in synchronization with the IS. The RM kinematic-parameters (latency, velocity, duration and amplitude) were analyzed using video-editing software and screen protractor. Patients were asked to rate the difficulty of their RMs in a numerical rating scale. In control trials, CD patients executed slower RMs (repeated measures ANOVA, p&lt;0.10(-5)), and reached a smaller final head position angle relative to the midline (p&lt;0.05), than CS. In test trials, SAS improved all RMs in both groups (p&lt;0.10(-14)). In addition, patients were more likely to reach beyond their baseline RM than CS (χ(2), p&lt;0.001) and rated their performance better than in control trials (t-test, p&lt;0.01). We found improvement of kinematic parameters and subjective perception of motor performance in CD patients with StartReact testing. Our results suggest that CD patients reach an adequate level of motor preparation before task execution.</description><subject>Acoustic Stimulation</subject><subject>Adult</subject><subject>Aged</subject><subject>Analysis</subject><subject>Auditory defects</subject><subject>Biology</subject><subject>Brain research</subject><subject>Care and treatment</subject><subject>Case-Control Studies</subject><subject>Clinical trials</subject><subject>Dystonia</subject><subject>Electrical stimuli</subject><subject>Electromyography</subject><subject>Female</subject><subject>Head Movements</subject><subject>Humans</subject><subject>Kinematics</subject><subject>Latency</subject><subject>Loudness Perception</subject><subject>Male</subject><subject>Medicine</subject><subject>Middle Aged</subject><subject>Motor neurons</subject><subject>Motor task performance</subject><subject>Movement disorders</subject><subject>Muscles</subject><subject>Músculs</subject><subject>Neck</subject><subject>Neurologia</subject><subject>Neurology</subject><subject>Neurosciences</subject><subject>Parkinson's disease</subject><subject>Patients</subject><subject>Perception</subject><subject>Psychomotor Performance</subject><subject>Reaction Time</subject><subject>Reaction time task</subject><subject>Synchronism</subject><subject>Synchronization</subject><subject>Test procedures</subject><subject>Torticollis - physiopathology</subject><subject>Trastorns motors</subject><subject>Variance analysis</subject><subject>Young Adult</subject><issn>1932-6203</issn><issn>1932-6203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUstqGzEUFaWlSd3-QWkHCqUbu3qMpNEmYEIfgUA3zVrIksaW0YxcPQz5-2riiUlKF0LSvece6Zx7AXiP4AoRjr7uQ4mj8qtDGO0KwpbRjr0Al0gQvGQYkpdPzhfgTUp7CCnpGHsNLjCBAlHRXYK7deNDMY0qxuUQ75uU3VB8SU042qjDYFNzDL6MWdXkUIODHXPj3eCyyi6MjRsbbePRaeUbc59yGJ16C171yif7bt4X4O77t9_XP5e3v37cXK9vl5oKkZddryyGqIN4g6GiRHOMuRGEmQ0VvZ1yjFrCFGRcY0ER1T21HDEhuMVYkAX4eOI9-JDk7EiSiGBGGSRV7wLcnBAmqL08RDdUHTIoJx8CIW6litlpbyUkPduwDUdQ9y3mbddjZAxSxHDMOEOV62p-rWwGa3Q1Iir_jPR5ZnQ7uQ1HSVo-_aUSoBOBTkXLaKtvWuWHwvNlWhhyLAnBHYe15sv8aAx_ik1ZDi5p670abShVK0KtoLClvEI__QP9vyOfT6itqqJ3Vvm8S7XDUzOTXLeiw7QjuK3Adv5tDClF25-VIiinEXykl9MIynkEa9mHpy6dix5njvwFbzHZCA</recordid><startdate>20121016</startdate><enddate>20121016</enddate><creator>Serranová, Tereza</creator><creator>Jech, Robert</creator><creator>Martí, Maria José</creator><creator>Modreanu, Raluca</creator><creator>Valldeoriola, Francesc</creator><creator>Sieger, Tomáš</creator><creator>Růžička, Evžen</creator><creator>Valls-Solé, Josep</creator><general>Public Library of Science</general><general>Public Library of Science (PLoS)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7QO</scope><scope>7RV</scope><scope>7SN</scope><scope>7SS</scope><scope>7T5</scope><scope>7TG</scope><scope>7TM</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>KB0</scope><scope>KL.</scope><scope>L6V</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PATMY</scope><scope>PDBOC</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PIMPY</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>RC3</scope><scope>7X8</scope><scope>XX2</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20121016</creationdate><title>A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia</title><author>Serranová, Tereza ; Jech, Robert ; Martí, Maria José ; Modreanu, Raluca ; Valldeoriola, Francesc ; Sieger, Tomáš ; Růžička, Evžen ; Valls-Solé, Josep</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c599t-8fae201802b20a53c7227d936db59fee20165e36a067c29515cf5e716997e2293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acoustic Stimulation</topic><topic>Adult</topic><topic>Aged</topic><topic>Analysis</topic><topic>Auditory defects</topic><topic>Biology</topic><topic>Brain research</topic><topic>Care and treatment</topic><topic>Case-Control Studies</topic><topic>Clinical trials</topic><topic>Dystonia</topic><topic>Electrical stimuli</topic><topic>Electromyography</topic><topic>Female</topic><topic>Head Movements</topic><topic>Humans</topic><topic>Kinematics</topic><topic>Latency</topic><topic>Loudness Perception</topic><topic>Male</topic><topic>Medicine</topic><topic>Middle Aged</topic><topic>Motor neurons</topic><topic>Motor task performance</topic><topic>Movement disorders</topic><topic>Muscles</topic><topic>Músculs</topic><topic>Neck</topic><topic>Neurologia</topic><topic>Neurology</topic><topic>Neurosciences</topic><topic>Parkinson's disease</topic><topic>Patients</topic><topic>Perception</topic><topic>Psychomotor Performance</topic><topic>Reaction Time</topic><topic>Reaction time task</topic><topic>Synchronism</topic><topic>Synchronization</topic><topic>Test procedures</topic><topic>Torticollis - physiopathology</topic><topic>Trastorns motors</topic><topic>Variance analysis</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Serranová, Tereza</creatorcontrib><creatorcontrib>Jech, Robert</creatorcontrib><creatorcontrib>Martí, Maria José</creatorcontrib><creatorcontrib>Modreanu, Raluca</creatorcontrib><creatorcontrib>Valldeoriola, Francesc</creatorcontrib><creatorcontrib>Sieger, Tomáš</creatorcontrib><creatorcontrib>Růžička, Evžen</creatorcontrib><creatorcontrib>Valls-Solé, Josep</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>ProQuest Nursing and Allied Health Journals</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Meteorological &amp; Geoastrophysical Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science &amp; Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies &amp; Aerospace Database‎ (1962 - current)</collection><collection>ProQuest Agriculture &amp; Environmental Science Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Materials Science Database</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Meteorological &amp; Geoastrophysical Abstracts - Academic</collection><collection>ProQuest Engineering Collection</collection><collection>Biological Sciences</collection><collection>Agricultural Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest Engineering Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest advanced technologies &amp; aerospace journals</collection><collection>ProQuest Advanced Technologies &amp; Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environmental Science Database</collection><collection>Materials Science Collection</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest Health &amp; Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health &amp; Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied &amp; Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Engineering collection</collection><collection>Environmental Science Collection</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Recercat</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>PloS one</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Serranová, Tereza</au><au>Jech, Robert</au><au>Martí, Maria José</au><au>Modreanu, Raluca</au><au>Valldeoriola, Francesc</au><au>Sieger, Tomáš</au><au>Růžička, Evžen</au><au>Valls-Solé, Josep</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia</atitle><jtitle>PloS one</jtitle><addtitle>PLoS One</addtitle><date>2012-10-16</date><risdate>2012</risdate><volume>7</volume><issue>10</issue><spage>e46586</spage><epage>e46586</epage><pages>e46586-e46586</pages><issn>1932-6203</issn><eissn>1932-6203</eissn><abstract>Patients with cervical dystonia (CD) present with an impaired performance of voluntary neck movements, which are usually slow and limited. We hypothesized that such abnormality could involve defective preparation for task execution. Therefore, we examined motor preparation in CD patients using the StartReact method. In this test, a startling auditory stimulus (SAS) is delivered unexpectedly at the time of the imperative signal (IS) in a reaction time task to cause a faster execution of the prepared motor programme. We expected that CD patients would show an abnormal StartReact phenomenon. Fifteen CD patients and 15 age matched control subjects (CS) were asked to perform a rotational movement (RM) to either side as quick as possible immediately after IS perception (a low intensity electrical stimulus to the II finger). In randomly interspersed test trials (25%) a 130 dB SAS was delivered simultaneously with the IS. We recorded RMs in the horizontal plane with a high speed video camera (2.38 ms per frame) in synchronization with the IS. The RM kinematic-parameters (latency, velocity, duration and amplitude) were analyzed using video-editing software and screen protractor. Patients were asked to rate the difficulty of their RMs in a numerical rating scale. In control trials, CD patients executed slower RMs (repeated measures ANOVA, p&lt;0.10(-5)), and reached a smaller final head position angle relative to the midline (p&lt;0.05), than CS. In test trials, SAS improved all RMs in both groups (p&lt;0.10(-14)). In addition, patients were more likely to reach beyond their baseline RM than CS (χ(2), p&lt;0.001) and rated their performance better than in control trials (t-test, p&lt;0.01). We found improvement of kinematic parameters and subjective perception of motor performance in CD patients with StartReact testing. Our results suggest that CD patients reach an adequate level of motor preparation before task execution.</abstract><cop>United States</cop><pub>Public Library of Science</pub><pmid>23091598</pmid><doi>10.1371/journal.pone.0046586</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1932-6203
ispartof PloS one, 2012-10, Vol.7 (10), p.e46586-e46586
issn 1932-6203
1932-6203
language eng
recordid cdi_plos_journals_1326560305
source Publicly Available Content (ProQuest); PubMed Central
subjects Acoustic Stimulation
Adult
Aged
Analysis
Auditory defects
Biology
Brain research
Care and treatment
Case-Control Studies
Clinical trials
Dystonia
Electrical stimuli
Electromyography
Female
Head Movements
Humans
Kinematics
Latency
Loudness Perception
Male
Medicine
Middle Aged
Motor neurons
Motor task performance
Movement disorders
Muscles
Músculs
Neck
Neurologia
Neurology
Neurosciences
Parkinson's disease
Patients
Perception
Psychomotor Performance
Reaction Time
Reaction time task
Synchronism
Synchronization
Test procedures
Torticollis - physiopathology
Trastorns motors
Variance analysis
Young Adult
title A loud auditory stimulus overcomes voluntary movement limitation in cervical dystonia
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-24T04%3A21%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_plos_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20loud%20auditory%20stimulus%20overcomes%20voluntary%20movement%20limitation%20in%20cervical%20dystonia&rft.jtitle=PloS%20one&rft.au=Serranov%C3%A1,%20Tereza&rft.date=2012-10-16&rft.volume=7&rft.issue=10&rft.spage=e46586&rft.epage=e46586&rft.pages=e46586-e46586&rft.issn=1932-6203&rft.eissn=1932-6203&rft_id=info:doi/10.1371/journal.pone.0046586&rft_dat=%3Cgale_plos_%3EA498258324%3C/gale_plos_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c599t-8fae201802b20a53c7227d936db59fee20165e36a067c29515cf5e716997e2293%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1326560305&rft_id=info:pmid/23091598&rft_galeid=A498258324&rfr_iscdi=true