High prevalence of vitamin D insufficiency in China: relationship with the levels of parathyroid hormone and markers of bone turnover

There is a lack of large-scale studies on vitamin D status and its relationship to parathyroid hormone (PTH) and bone turnover markers in adults living in Shanghai. The objectives were to determine the prevalence of vitamin D insufficiency in Shanghai and to investigate the relationship of 25(OH)D w...

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Bibliographic Details
Published in:PloS one 2012-11, Vol.7 (11), p.e47264-e47264
Main Authors: Lu, Han-Kui, Zhang, Zeng, Ke, Yao-Hua, He, Jin-Wei, Fu, Wen-Zhen, Zhang, Chang-Qing, Zhang, Zhen-Lin
Format: Article
Language:English
Subjects:
Adult
Adults
Aged
Aged, 80 and over
Albumin
Biology
Biomarkers - blood
Bone and Bones - metabolism
Bone density
Bone diseases
Bone surgery
Bone turnover
China - epidemiology
Cross-Sectional Studies
Female
Females
Genetic research
Hospitals
Humans
Lifestyles
Liver
Male
Males
Markers
Medicine
Mens health
Metabolism
Middle Aged
Normal distribution
Older people
Orthopedics
Osteoporosis
Parathyroid
Parathyroid hormone
Parathyroid Hormone - blood
Parathyroid hormones
Population
Prevalence
Type 2 diabetes
Vitamin D
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - epidemiology
Vitamin D Deficiency - metabolism
Vitamin deficiency
Womens health
Young Adult
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Summary:There is a lack of large-scale studies on vitamin D status and its relationship to parathyroid hormone (PTH) and bone turnover markers in adults living in Shanghai. The objectives were to determine the prevalence of vitamin D insufficiency in Shanghai and to investigate the relationship of 25(OH)D with parathyroid function and bone turnover markers. This cross-sectional study involved 649 men and 1939 women aged 20-89 years who were randomly sampled in Shanghai. Serum concentrations of 25(OH)D, PTH, albumin, and bone turnover markers were measured. During the winter season, the prevalence of vitamin D insufficiency (
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0047264