Trends in low-density lipoprotein cholesterol goal achievement in high risk United States adults: longitudinal findings from the 1999-2008 National Health and Nutrition Examination Surveys

Previous studies have demonstrated gaps in achievement of low-density lipoprotein-cholesterol (LDL-C) goals among U.S. individuals at high cardiovascular disease risk; however, recent studies in selected populations indicate improvements. We sought to define the longitudinal trends in achieving LDL-...

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Bibliographic Details
Published in:PloS one 2013-04, Vol.8 (4), p.e59309-e59309
Main Authors: Tattersall, Matthew C, Gangnon, Ronald E, Karmali, Kunal N, Cullen, Michael W, Stein, James H, Keevil, Jon G
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adults
Aged
Aged, 80 and over
Biology
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - history
Cholesterol
Cholesterol, LDL - blood
Coronary artery disease
Diabetes
Female
Health aspects
Health risk assessment
Health risks
Heart
Heart diseases
High density lipoprotein
History, 20th Century
History, 21st Century
Humans
Lipoproteins (low density)
Longitudinal Studies
Low density lipoprotein
Low density lipoproteins
Male
Medicine
Middle Aged
Nutrition
Nutrition Surveys - statistics & numerical data
Polls & surveys
Population studies
Population Surveillance
Prevalence
Reference Values
Risk
Risk factors
Stroke
Subgroups
Surveys
Trends
United States - epidemiology
Young Adult
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Summary:Previous studies have demonstrated gaps in achievement of low-density lipoprotein-cholesterol (LDL-C) goals among U.S. individuals at high cardiovascular disease risk; however, recent studies in selected populations indicate improvements. We sought to define the longitudinal trends in achieving LDL-C goals among high-risk United States adults from 1999-2008. We analyzed five sequential population-based cross-sectional National Health and Nutrition Examination Surveys 1999-2008, which included 18,656 participants aged 20-79 years. We calculated rates of LDL-C goal achievement and treatment in the high-risk population. The prevalence of high-risk individuals increased from 13% to 15.5% (p = 0.046). Achievement of LDL-C
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0059309