Longitudinal replication studies of GWAS risk SNPs influencing body mass index over the course of childhood and adulthood

Genome-wide association studies (GWAS) have identified multiple common variants associated with body mass index (BMI). In this study, we tested 23 genotyped GWAS-significant SNPs (p-value

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Bibliographic Details
Published in:PloS one 2012-02, Vol.7 (2), p.e31470-e31470
Main Authors: Mei, Hao, Chen, Wei, Jiang, Fan, He, Jiang, Srinivasan, Sathanur, Smith, Erin N, Schork, Nicholas, Murray, Sarah, Berenson, Gerald S
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adults
Age
AP-2 protein
Apoptosis
Biology
Birth weight
Birth Weight - genetics
Body Composition
Body mass
Body Mass Index
Brain
Brain-derived neurotrophic factor
Child
Child, Preschool
Childhood
Children
Children & youth
Diabetes
Endocrinology
Epidemiology
Families & family life
Female
Fetal development
Follow-Up Studies
Genes
Genetic Predisposition to Disease
Genome-Wide Association Study
Genomes
Genomics
Genotype
Humans
Kinases
Longitudinal Studies
Male
Medicine
Metabolism
Obesity
Obesity - genetics
Pediatrics
Personal health
Physiological aspects
Polymorphism, Single Nucleotide - genetics
Public health
Risk Factors
Science
Signal transduction
Single nucleotide polymorphisms
Single-nucleotide polymorphism
Statistical methods
Studies
Transcription factors
Type 2 diabetes
Young Adult
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Description
Summary:Genome-wide association studies (GWAS) have identified multiple common variants associated with body mass index (BMI). In this study, we tested 23 genotyped GWAS-significant SNPs (p-value
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0031470